Extracellular vesicles in cancer nanomedicine
Tarasov V. V., Svistunov A. A., Chubarev V. N., Dostdar S. A., Sokolov A. V., Brzecka A., Sukocheva O., Neganova M. E., Klochkov S. G., Somasundaram S. G., Kirkland C. E., Aliev G.
Seminars in Cancer Biology
Опубликовано: 2019
Тип ресурса: Обзор
DOI:10.1016/j.semcancer.2019.08.017
Аннотация:
To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail. © 2019 Elsevier Ltd
Ключевые слова:
Cancer; Exosomes; Extracellular vesicles; Nanodrug delivery; Vaccines
Язык текста: Английский
ISSN: 1096-3650
Tarasov V. V. Vadim Vladimirovich 1987-
Svistunov A. A. Andrej Alekseevich 1965-
Chubarev V. N. Vladimir Nikolaevich 1954-
Dostdar S. A. Samira Aziz 1997-
Sokolov A. V.
Brzecka A.
Sukocheva O.
Neganova M. E.
Klochkov S. G.
Somasundaram S. G.
Kirkland C. E.
Aliev G. Gyumrakh 1958-
Тарасов В. В. Вадим Владимирович 1987-
Свистунов А. А. Андрей Алексеевич 1965-
Чубарев В. Н. Владимир Николаевич 1954-
Достдар С. А. Самира Азиз 1997-
Соколов А. В.
Брзеcка А.
Сукочева О.
Неганова М. Е.
Клочков С. Г.
Сомасундарам С. Г.
Киркланд C. Е.
Алиев Г. Гюмрах 1958-
Extracellular vesicles in cancer nanomedicine
Текст визуальный непосредственный
Seminars in Cancer Biology
Academic Press
Обзор
Cancer Exosomes Extracellular vesicles Nanodrug delivery Vaccines
To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail. © 2019 Elsevier Ltd