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Withdrawal of inhaled corticosteroids in patients with chronic obstructive pulmonary disease [Отмена ингаляционных глюкокортикостероидов у...

Авдеев С. Н., Аисанов З. Р., Архипов В. В., Белевскиy А. С., Лешченко И. В., Овчаренко С. И., Шмелев Е. И., Миравитлс М.
Пульмонология
Т. 29, Вып. 3, С. 334-345
Опубликовано: 2019
Тип ресурса: Статья

DOI:10.18093/0869-0189-2019-29-3-334-345

Аннотация:
According to current clinical guidelines, a role of inhaled corticosteroids (ICS) in the management of patients with COPD is limited. The optimal benefit/risk ratio could be achieved only in specific populations of patients with COPD. In a real life, physicians often do not follow clinical guidelines, and ICS are overprescribed. In addition to the lack of effectiveness, there are possible risks of ICS use. Regarding to this, there is a need to develop a simple and convenient algorithm for ICS withdrawal in the population of COPD patients who do not fit criteria for therapy with ICS. Clinical studies on efficacy and safety of ICS and available data on ICS withdrawal in patients with COPD are analyzed in this article. An international expert panel developed a simple and convenient algorithm for withdrawal of ICS in patients with COPD based on published data. © 2019 Medical Education. All rights reserved.
Ключевые слова:
Chronic obstructive pulmonary disease; ICS withdrawal algorithm; Inhaled corticosteroids; Inhaled drugs; Long-acting Bron-chodilators; Withdrawal of inhaled corticosteroids
corticosteroid; Article; chronic obstructive lung disease; clinical effectiveness; drug efficacy; drug safety; drug withdrawal; human; practice guideline; risk benefit analysis
Язык текста: Русский
ISSN: 0869-0189
Авдеев С. Н. Сергей Николаевич 1968-
Аисанов З. Р.
Архипов В. В.
Белевскиy А. С.
Лешченко И. В.
Овчаренко С. И. Светлана Ивановна 1937-
Шмелев Е. И.
Миравитлс М.
Avdeev S. N. Sergej Nikolaevich 1968-
Aisanov Z. R.
Arkhipov V. V.
Belevskiy A. S.
Leshchenko I. V.
Ovcharenko S. I. Svetlana Ivanovna 1937-
Shmelev E. I.
Miravitls M.
Withdrawal of inhaled corticosteroids in patients with chronic obstructive pulmonary disease [Отмена ингаляционных глюкокортикостероидов у пациентов с хронической обструктивной болезнью легких]
Withdrawal of inhaled corticosteroids in patients with chronic obstructive pulmonary disease [Отмена ингаляционных глюкокортикостероидов у...
Текст визуальный непосредственный
Пульмонология
Научно-практический журнал "Пульмонология"
Т. 29, Вып. 3 С. 334-345
2019
Статья
Chronic obstructive pulmonary disease ICS withdrawal algorithm Inhaled corticosteroids Inhaled drugs Long-acting Bron-chodilators Withdrawal of inhaled corticosteroids
corticosteroid Article chronic obstructive lung disease clinical effectiveness drug efficacy drug safety drug withdrawal human practice guideline risk benefit analysis
According to current clinical guidelines, a role of inhaled corticosteroids (ICS) in the management of patients with COPD is limited. The optimal benefit/risk ratio could be achieved only in specific populations of patients with COPD. In a real life, physicians often do not follow clinical guidelines, and ICS are overprescribed. In addition to the lack of effectiveness, there are possible risks of ICS use. Regarding to this, there is a need to develop a simple and convenient algorithm for ICS withdrawal in the population of COPD patients who do not fit criteria for therapy with ICS. Clinical studies on efficacy and safety of ICS and available data on ICS withdrawal in patients with COPD are analyzed in this article. An international expert panel developed a simple and convenient algorithm for withdrawal of ICS in patients with COPD based on published data. © 2019 Medical Education. All rights reserved.