Alcohol use disorders
Carvalho A. F., Heilig M., Perez A., Probst C., Rem Yu.
The Lancet
Vol.394, Issue10200, P. 781-792
Опубликовано: 2019
Тип ресурса: Обзор
DOI:10.1016/S0140-6736(19)31775-1
Аннотация:
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or injury. Despite their high prevalence, alcohol use disorders are undertreated partly because of the high stigma associated with them, but also because of insufficient systematic screening in primary health care, although effective and cost-effective psychosocial and pharmacological interventions do exist. Primary health care should be responsible for most treatment, with routine screening for alcohol use, and the provision of a staggered treatment response, from brief advice to pharmacological treatment. Clinical interventions for these disorders should be embedded in a supportive environment, whi
Ключевые слова:
acamprosate; baclofen; disulfiram; gabapentin; nalmefene; naltrexone; ondansetron; oxybate sodium; topiramate; varenicline; abdominal pain; alcohol consumption; alcoholism; arthralgia; confusion; diarrhea; dizziness; drowsiness; DSM-5; genetic risk; headache; health care policy; human; injection site reaction; insomnia; libido disorder; liver toxicity; metallic taste; mood disorder; mortality rate; myalgia; nausea and vomiting; neuropathy; optic neuritis; prevalence; primary health care; priority journal; pruritus; psychosis; rash; restlessness; Review; risk factor; screening test; treatment response; alcoholism; cost of illness; female; genetics; global health; male; mass screening; procedures; Alcoholism; Cost of Illness; Female; Global Health; Humans; Male; Mass Screening; Primary Health Care
Язык текста: Английский
ISSN: 1474-547X
Carvalho A. F.
Heilig M.
Perez A.
Probst C.
Rem Yu. Yurgen 1958-
Cарвалхо А. Ф.
Хеилиг М.
Перез А.
Пробст C.
Рем Ю. Юрген 1958-
Alcohol use disorders
Текст визуальный непосредственный
The Lancet
Elsevier Science Publisher B.V.
Vol.394, Issue10200 P. 781-792
2019
Обзор
acamprosate baclofen disulfiram gabapentin nalmefene naltrexone ondansetron oxybate sodium topiramate varenicline abdominal pain alcohol consumption alcoholism arthralgia confusion diarrhea dizziness drowsiness DSM-5 genetic risk headache health care policy human injection site reaction insomnia libido disorder liver toxicity metallic taste mood disorder mortality rate myalgia nausea and vomiting neuropathy optic neuritis prevalence primary health care priority journal pruritus psychosis rash restlessness Review risk factor screening test treatment response alcoholism cost of illness female genetics global health male mass screening procedures Alcoholism Cost of Illness Female Global Health Humans Male Mass Screening Primary Health Care
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or injury. Despite their high prevalence, alcohol use disorders are undertreated partly because of the high stigma associated with them, but also because of insufficient systematic screening in primary health care, although effective and cost-effective psychosocial and pharmacological interventions do exist. Primary health care should be responsible for most treatment, with routine screening for alcohol use, and the provision of a staggered treatment response, from brief advice to pharmacological treatment. Clinical interventions for these disorders should be embedded in a supportive environment, whi