Pancreatic calcifications associate with diverse aetiological risk factors in patients with chronic pancreatitis: A multicentre study of 1500 cases
Olesen S. S., Lisitskaya M. V., Drewes A. M., Novovic S., Nøjgaard C., Kalaitzakis E., Jensen N. M., Engjom T., Erchinger F., Waage A., Hauge T., Haas S. L., Vujasinovic M., Lindkvist B., Zviniene K., Pukitis A., Ozola-Zālīte I., Okhloby'stin A. V., Parhiala M., Laukkarinen J., Frøkjær J. B.
Pancreatology
Vol.19, Issue7, P. 922-928
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1016/j.pan.2019.08.009
Аннотация:
Background: Pancreatic calcifications is a common finding in patients with chronic pancreatitis (CP), but the underlying pathophysiology is incompletely understood. Past studies for risk factors of calcifications have generally been focused on single parameters or limited by small sample sizes. The aim of this study was to explore several patient and disease characteristics and their associations with pancreatic calcifications in a large cohort of CP patients with diverse aetiological risk factors. Methods: This was a multicentre, cross-sectional study including 1509 patients with CP. Patient and disease characteristics were compared for patients with calcifications (n = 912) vs. without calcifications (n = 597). Multivariable logistic regression was performed to assess the parameters independently associated with calcifications. Results: The mean age of patients was 53.9 ± 14.5 years and 1006 (67[%]) were men. The prevalence of calcifications was 60.4[%] in the overall patient cohort, but
Ключевые слова:
Alcohol; Calcifications; Chronic pancreatitis; Endoscopy; Smoking; Surgery
alcohol; adult; Article; chronic pancreatitis; cohort analysis; cross-sectional study; diabetes mellitus; disease association; endoscopic surgery; female; human; major clinical study; male; middle aged; pancreas calcification; prevalence; priority journal; risk factor; smoking; aged; calcinosis; chronic pancreatitis; clinical trial; complication; multicenter study; risk factor; Adult; Aged; Calcinosis; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Pancreatitis, Chronic; Risk Factors
Язык текста: Английский
ISSN: 1424-3911
Olesen S. S.
Lisitskaya M. V.
Drewes A. M.
Novovic S.
Nøjgaard C.
Kalaitzakis E.
Jensen N. M.
Engjom T.
Erchinger F.
Waage A.
Hauge T.
Haas S. L.
Vujasinovic M.
Lindkvist B.
Zviniene K.
Pukitis A.
Ozola-Zālīte I.
Okhloby'stin A. V. Aleksej Viktorovich 1967-
Parhiala M.
Laukkarinen J.
Frøkjær J. B.
Олесен С. С.
Лисицкайа М. В.
Дреwес А. М.
Нововиc С.
Нøйгаард C.
Калаитзакис Е.
Йенсен Н. М.
Енгйом Т.
Ерчингер Ф.
Wааге А.
Хауге Т.
Хаас С. Л.
Вуйасиновиc М.
Линдквист Б.
Звиниене К.
Пукитис А.
Озола-Зāлīте И.
Охлобыстин А. В. Алексей Викторович 1967-
Пархиала М.
Лауккаринен Й.
Фрøкйæр Й. Б.
Pancreatic calcifications associate with diverse aetiological risk factors in patients with chronic pancreatitis: A multicentre study of 1500 cases
Текст визуальный непосредственный
Pancreatology
S. Karger AG
Vol.19, Issue7 P. 922-928
2019
Статья
Alcohol Calcifications Chronic pancreatitis Endoscopy Smoking Surgery
alcohol adult Article chronic pancreatitis cohort analysis cross-sectional study diabetes mellitus disease association endoscopic surgery female human major clinical study male middle aged pancreas calcification prevalence priority journal risk factor smoking aged calcinosis chronic pancreatitis clinical trial complication multicenter study risk factor Adult Aged Calcinosis Cohort Studies Cross-Sectional Studies Female Humans Male Middle Aged Pancreatitis, Chronic Risk Factors
Background: Pancreatic calcifications is a common finding in patients with chronic pancreatitis (CP), but the underlying pathophysiology is incompletely understood. Past studies for risk factors of calcifications have generally been focused on single parameters or limited by small sample sizes. The aim of this study was to explore several patient and disease characteristics and their associations with pancreatic calcifications in a large cohort of CP patients with diverse aetiological risk factors. Methods: This was a multicentre, cross-sectional study including 1509 patients with CP. Patient and disease characteristics were compared for patients with calcifications (n = 912) vs. without calcifications (n = 597). Multivariable logistic regression was performed to assess the parameters independently associated with calcifications. Results: The mean age of patients was 53.9 ± 14.5 years and 1006 (67[%]) were men. The prevalence of calcifications was 60.4[%] in the overall patient cohort, but