Аннотация:
The purpose of the overview is to analyze the role of apoptosis in the pathogenesis of critical illness and discuss specific features of contributed biochemical processes. The paper reviews 117 publications, 76 of which were published during the recent five years. Published data show that the ability to control endogenic apoptotic processes offers opportunities for the development of functional therapy approaches to various diseases. © 2019, V.A. Negovsky Research Institute of General Reanimatology. All rights reserved.
Ключевые слова:
Apoptosis; Biochemical mechanisms; Cell death; Damage
antioxidant; apoptosome; apoptotic protease activating factor 1; calmodulin binding protein; calpain; caspase 3; caspase 8; caspase 9; CD40 antigen; CD8 antigen; cysteine proteinase; cytochrome; effector caspase; endonuclease; glucocorticoid; heat shock protein; heat shock protein 70; inhibitor of apoptosis protein; inhibitor protein; interleukin 1; mitogen activated protein kinase 14; phosphatidylserine; phospholipid; polypeptide antibiotic agent; procaspase 3; protein bcl x; reactive oxygen metabolite; tumor necrosis factor; tumor necrosis factor receptor superfamily member 6; acute kidney failure; antiapoptotic activity; apoptosis; B cell lymphoma cell; biochemical analysis; cell activity; cell cycle; cell proliferation; chromatin; critical illness; cytoskeleton; cytotoxicity; DNA fragmentation; Enterococcus faecalis; extracellular space; human; inflammation; mitochondrial biogenesis; nerve cell; oxidative stress; pathogenesis; pathophysiology; protein degradation; reperfusion; resp
Глухов А. И. Александр Иванович 1958-
Грызунова Г. К. Галина Константиновна 1949-
Усаи Л. И.
Алейникова Т. Л. Татьяна Леонидовна 1937-
Черникова Н. В. Наталия Викторовна 1964-
Бурт А. Ю. Андрей Юрьевич 1956-
Glukhov A. I. Aleksandr Ivanovich 1958-
Gry'zunova G. K. Galina Konstantinovna 1949-
Usai L. I.
Alejnikova T. L. Tat`yana Leonidovna 1937-
Chernikova N. V. Nataliya Viktorovna 1964-
Burt A. Yu. Andrej Yuryevich 1956-
The role of apoptosis in the pathogenic mechanism of critical states (Review)
Текст визуальный непосредственный
Общая реаниматология
Некоммерческая организация Фонд "Медицина критических состояний"
Т. 15, Вып. 2 С. 79-98
2019
Обзор
Apoptosis Biochemical mechanisms Cell death Damage
antioxidant apoptosome apoptotic protease activating factor 1 calmodulin binding protein calpain caspase 3 caspase 8 caspase 9 CD40 antigen CD8 antigen cysteine proteinase cytochrome effector caspase endonuclease glucocorticoid heat shock protein heat shock protein 70 inhibitor of apoptosis protein inhibitor protein interleukin 1 mitogen activated protein kinase 14 phosphatidylserine phospholipid polypeptide antibiotic agent procaspase 3 protein bcl x reactive oxygen metabolite tumor necrosis factor tumor necrosis factor receptor superfamily member 6 acute kidney failure antiapoptotic activity apoptosis B cell lymphoma cell biochemical analysis cell activity cell cycle cell proliferation chromatin critical illness cytoskeleton cytotoxicity DNA fragmentation Enterococcus faecalis extracellular space human inflammation mitochondrial biogenesis nerve cell oxidative stress pathogenesis pathophysiology protein degradation reperfusion resp
The purpose of the overview is to analyze the role of apoptosis in the pathogenesis of critical illness and discuss specific features of contributed biochemical processes. The paper reviews 117 publications, 76 of which were published during the recent five years. Published data show that the ability to control endogenic apoptotic processes offers opportunities for the development of functional therapy approaches to various diseases. © 2019, V.A. Negovsky Research Institute of General Reanimatology. All rights reserved.