Аннотация:
Background. Cerebral venous thrombosis is a rare, but life-threatening condition that is now becoming increasingly common in obstetric and gynecological practice due to the widespread use of hormone therapy and assisted reproductive technologies. Description. The paper presents a clinical case of cerebral sinus thrombosis during pregnancy after cryopreserved in vitro fertilization. It analyzes risk factors for cerebral venous thrombosis during pregnancy, the validity of pregnancy management tactics, and the choice of anticoagulant therapy. Conclusion. Cerebral thrombosis can develop in the absence of classical thrombophilia in the presence of antithrombin III deficiency and imbalance in the von Willebrand factor/ADAMTS13 system due to hyperestrogenia. Adequately chosen anticoagulant therapy in patients after cerebrovascular thrombosis prevents recurrences, the development of thrombosis of other localizations, and placenta-associated pregnancy complications. © 2019, Bionika Media Ltd..
Ключевые слова:
Anticoagulant therapy; Assisted reproductive technologies; Cerebral venous thrombosis; Hemostatic disorders; Low-molecular-weight heparin; Pregnancy; Thrombophilia; Thrombophilia
anticoagulant agent; anticoagulant therapy; Article; cerebral sinus thrombosis; cryopreservation; female; high risk pregnancy; human; in vitro fertilization; managed care; pregnancy; pregnancy complication; risk assessment; risk factor
Акиньшина С. В. Светлана Владимировна 0001-
Елалами И.
Воробьев А. В. Александр Викторович 1979-
Бицадзе В. О. Виктория Омаровна 1970-
Akin`shina S. V. Svetlana Vladimirovna 0001-
Elalami I.
Vorobyev A. V. Aleksandr Viktorovich 1979-
Bitsadze V. O. Viktoriya Omarovna 1970-
A clinical case of cerebral sinus thrombosis during pregnancy after cryopreserved in vitro fertilization
Текст визуальный непосредственный
Акушерство и гинекология
Бионика Медиа
Т. 2019, Вып. 9 С. 192-197
2019
Статья
Anticoagulant therapy Assisted reproductive technologies Cerebral venous thrombosis Hemostatic disorders Low-molecular-weight heparin Pregnancy Thrombophilia Thrombophilia
anticoagulant agent anticoagulant therapy Article cerebral sinus thrombosis cryopreservation female high risk pregnancy human in vitro fertilization managed care pregnancy pregnancy complication risk assessment risk factor
Background. Cerebral venous thrombosis is a rare, but life-threatening condition that is now becoming increasingly common in obstetric and gynecological practice due to the widespread use of hormone therapy and assisted reproductive technologies. Description. The paper presents a clinical case of cerebral sinus thrombosis during pregnancy after cryopreserved in vitro fertilization. It analyzes risk factors for cerebral venous thrombosis during pregnancy, the validity of pregnancy management tactics, and the choice of anticoagulant therapy. Conclusion. Cerebral thrombosis can develop in the absence of classical thrombophilia in the presence of antithrombin III deficiency and imbalance in the von Willebrand factor/ADAMTS13 system due to hyperestrogenia. Adequately chosen anticoagulant therapy in patients after cerebrovascular thrombosis prevents recurrences, the development of thrombosis of other localizations, and placenta-associated pregnancy complications. © 2019, Bionika Media Ltd..