Creating a neuroprosthesis for active tactile exploration of textures
O’Doherty J. E., Shokur S., Medina L. E., Lebedev M. A., Nicolelis M. A. L.
Proceedings of the National Academy of Sciences of the United States of America
Vol.116, Issue43, P. 21821-21827
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1073/pnas.1908008116
Аннотация:
Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, thus, has potential as an approach to sensorize prosthetic limbs. However, it is not known whether ICMS could recreate active texture exploration—the ability to infer information about object texture by using one’s fingertips to scan a surface. Here, we show that ICMS of S1 can convey information about the spatial frequencies of invisible virtual gratings through a process of active tactile exploration. Two rhesus monkeys scanned pairs of visually identical screen objects with the fingertip of a hand avatar—controlled first via a joystick and later via a brain–machine interface—to find the object with denser virtual gratings. The gratings consisted of evenly spaced ridges that were signaled through individual ICMS pulses generated whenever the avatar’s fingertip crossed a ridge. The monkeys learned to interpret these ICMS patterns, evoked by the interpla
Ключевые слова:
Brain–machine interface; Neuroprosthetics; Sensory feedback
adult; animal experiment; Article; controlled study; differential threshold; intracortical microstimulation; just noticeable difference; nervous system parameters; nonhuman; priority journal; rhesus monkey; sensory discrimination task; signal transduction; tactile discrimination; tactile feedback; tactile stimulation; task performance
Язык текста: Английский
ISSN: 1091-6490
O’Doherty J. E.
Shokur S.
Medina L. E.
Lebedev M. A. Mikhail Aleksandrovich 1954-
Nicolelis M. A. L.
О’Дохертy Й. Е.
Шокур С.
Медина Л. Е.
Лебедев М. А. Михаил Александрович 1954-
Ниcолелис М. А. Л.
Creating a neuroprosthesis for active tactile exploration of textures
Текст визуальный непосредственный
Proceedings of the National Academy of Sciences of the United States of America
Proquest Academic Research Library
Vol.116, Issue43 P. 21821-21827
2019
Статья
Brain–machine interface Neuroprosthetics Sensory feedback
adult animal experiment Article controlled study differential threshold intracortical microstimulation just noticeable difference nervous system parameters nonhuman priority journal rhesus monkey sensory discrimination task signal transduction tactile discrimination tactile feedback tactile stimulation task performance
Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, thus, has potential as an approach to sensorize prosthetic limbs. However, it is not known whether ICMS could recreate active texture exploration—the ability to infer information about object texture by using one’s fingertips to scan a surface. Here, we show that ICMS of S1 can convey information about the spatial frequencies of invisible virtual gratings through a process of active tactile exploration. Two rhesus monkeys scanned pairs of visually identical screen objects with the fingertip of a hand avatar—controlled first via a joystick and later via a brain–machine interface—to find the object with denser virtual gratings. The gratings consisted of evenly spaced ridges that were signaled through individual ICMS pulses generated whenever the avatar’s fingertip crossed a ridge. The monkeys learned to interpret these ICMS patterns, evoked by the interpla