Increased pain sensitivity in obese patients after lung cancer surgery
Majchrzak M., Brzecka A., Daroszewski C., Błasiak P., Rzechonek A., Tarasov V. V., Chubarev V. N., Kurinnaya A. S., Mel`nikova T. I., Makhmutova A., Klochkov S. G., Somasundaram S. G., Kirkland C. E., Aliev G.
Frontiers in Pharmacology
Vol.10, IssueJUN, Num.626
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.3389/fphar.2019.00626
Аннотация:
Background: Obesity and cancer are recognized worldwide health threats. While there is no reported causal relationship, the increasing frequency of both conditions results in a higher incidence of obese patients who are being treated for cancer. Physiological data indicate that there is a relationship between obesity and susceptibility to pain; however, currently, there are no specific pharmacological interventions. Objective: To evaluate the self-reported intensity of postoperative pain in obese and nonobese lung cancer who receive either thoracotomy or video-assisted thoracic surgery (VATS) surgical therapy. Material and Methods: In 50 obese [mean body mass index (BMI) of 34.1 ± 3.2 kg/m2] and 62 nonobese (mean BMI of 24.9 ± 3 kg/m2) lung cancer patients, the intensity of pain was estimated every 4 h using a visual analog scale (VAS, 0 indicating no pain and 10 indicating “worst imaginable pain”) beginning shortly after surgery (Day O) and continuing until the day of discharge (Day D
Ключевые слова:
Analgesics; Lung cancer; Obesity; Pain; Thoracotomy; Video-assisted thoracic surgery; Visual analog scale
adult; aged; Article; body mass; cancer surgery; clinical evaluation; clinical practice; controlled study; disease severity; female; human; length of stay; lung cancer; major clinical study; male; nociception; obese patient; operation duration; pain assessment; pain intensity; pain severity; postoperative pain; self report; thoracotomy; video assisted thoracoscopic surgery; visual analog scale
Язык текста: Английский
ISSN: 1663-9812
Majchrzak M.
Brzecka A.
Daroszewski C.
Błasiak P.
Rzechonek A.
Tarasov V. V. Vadim Vladimirovich 1987-
Chubarev V. N. Vladimir Nikolaevich 1954-
Kurinnaya A. S. Anastasiya Sergeevna 1995-
Mel`nikova T. I. Tat`yana Il`inichna 1958-
Makhmutova A.
Klochkov S. G.
Somasundaram S. G.
Kirkland C. E.
Aliev G. Gyumrakh 1958-
Майчрзак М.
Брзеcка А.
Даросзеwски C.
Бłасиак П.
Рзечонек А.
Тарасов В. В. Вадим Владимирович 1987-
Чубарев В. Н. Владимир Николаевич 1954-
Куринная А. С. Анастасия Сергеевна 1995-
Мельникова Т. И. Татьяна Ильинична 1958-
Махмутова А.
Клочков С. Г.
Сомасундарам С. Г.
Киркланд C. Е.
Алиев Г. Гюмрах 1958-
Increased pain sensitivity in obese patients after lung cancer surgery
Текст визуальный непосредственный
Frontiers in Pharmacology
Vol.10, IssueJUN Num.626
2019
Статья
Analgesics Lung cancer Obesity Pain Thoracotomy Video-assisted thoracic surgery Visual analog scale
adult aged Article body mass cancer surgery clinical evaluation clinical practice controlled study disease severity female human length of stay lung cancer major clinical study male nociception obese patient operation duration pain assessment pain intensity pain severity postoperative pain self report thoracotomy video assisted thoracoscopic surgery visual analog scale
Background: Obesity and cancer are recognized worldwide health threats. While there is no reported causal relationship, the increasing frequency of both conditions results in a higher incidence of obese patients who are being treated for cancer. Physiological data indicate that there is a relationship between obesity and susceptibility to pain; however, currently, there are no specific pharmacological interventions. Objective: To evaluate the self-reported intensity of postoperative pain in obese and nonobese lung cancer who receive either thoracotomy or video-assisted thoracic surgery (VATS) surgical therapy. Material and Methods: In 50 obese [mean body mass index (BMI) of 34.1 ± 3.2 kg/m2] and 62 nonobese (mean BMI of 24.9 ± 3 kg/m2) lung cancer patients, the intensity of pain was estimated every 4 h using a visual analog scale (VAS, 0 indicating no pain and 10 indicating “worst imaginable pain”) beginning shortly after surgery (Day O) and continuing until the day of discharge (Day D