Tapentadol vs oxycodone/naloxone in the management of pain after total hip arthroplasty in the fast track setting: an observational study
D’Amato T., Martorelli F., Fenocchio G., Simili V., Kon E., Di M. B., Scardino M.
Journal of Experimental Orthopaedics
Vol.6, Issue1, Num.36
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1186/s40634-019-0204-6
Аннотация:
Background: In recent years, joint replacement surgery has gradually progressed towards the fast-track model, and early rehabilitation immediately after surgery is regarded fundamental for optimal recovery of function: the aim of the present study is to describe the efficacy in perioperative management of pain in patients undergoing total hip replacement surgery and treated with tapentadol or oxycodone/naloxone in combination with ketoprofene. Methods: Single-center retrospective study on patients with moderate-severe pain, referred to total hip replacement. Patients received either tapentadol (100 mg/twice-daily post-surgery – treatment group) or oxycodone/naloxone (10 mg/5 mg post-surgery – control group) plus ketoprofen 100 mg/ twice daily. Supplemental analgesia (paracetamol 1 g or morphine 0,1 mg/kg sc) was provided if needed. Pain at rest and pain during movement were evaluated on a daily basis for 4 days post-op, after which patients were usually discharged. All adverse events w
Ключевые слова:
Fast track; Multimodal analgesia; Naloxone/oxycodone; Pain management; Tapentadol; Total hip replacement
ketoprofen; morphine; naloxone plus oxycodone; paracetamol; tapentadol; adult; aged; analgesia; Article; body movement; constipation; controlled study; drug efficacy; drug safety; drug tolerability; faintness; female; follow up; human; major clinical study; male; numeric rating scale; observational study; outcome assessment; pain intensity; paresthesia; postoperative nausea; postoperative pain; postoperative vomiting; priority journal; pruritus; rest; retrospective study; total hip replacement; treatment response; vomiting
Язык текста: Английский
ISSN: 2197-1153
D’Amato T.
Martorelli F.
Fenocchio G.
Simili V.
Kon E. Elizaveta 1969-
Di M. B. Matteo Berardo 1985-
Scardino M.
Д’Амато Т.
Марторелли Ф.
Феноcчио Г.
Симили В.
Кон Е. Елизавета 1969-
Ди М. Б. Маттео Берардо 1985-
Сcардино М.
Tapentadol vs oxycodone/naloxone in the management of pain after total hip arthroplasty in the fast track setting: an observational study
Текст визуальный непосредственный
Journal of Experimental Orthopaedics
Vol.6, Issue1 Num.36
2019
Статья
Fast track Multimodal analgesia Naloxone/oxycodone Pain management Tapentadol Total hip replacement
ketoprofen morphine naloxone plus oxycodone paracetamol tapentadol adult aged analgesia Article body movement constipation controlled study drug efficacy drug safety drug tolerability faintness female follow up human major clinical study male numeric rating scale observational study outcome assessment pain intensity paresthesia postoperative nausea postoperative pain postoperative vomiting priority journal pruritus rest retrospective study total hip replacement treatment response vomiting
Background: In recent years, joint replacement surgery has gradually progressed towards the fast-track model, and early rehabilitation immediately after surgery is regarded fundamental for optimal recovery of function: the aim of the present study is to describe the efficacy in perioperative management of pain in patients undergoing total hip replacement surgery and treated with tapentadol or oxycodone/naloxone in combination with ketoprofene. Methods: Single-center retrospective study on patients with moderate-severe pain, referred to total hip replacement. Patients received either tapentadol (100 mg/twice-daily post-surgery – treatment group) or oxycodone/naloxone (10 mg/5 mg post-surgery – control group) plus ketoprofen 100 mg/ twice daily. Supplemental analgesia (paracetamol 1 g or morphine 0,1 mg/kg sc) was provided if needed. Pain at rest and pain during movement were evaluated on a daily basis for 4 days post-op, after which patients were usually discharged. All adverse events w