Аннотация:
Skin lesion with S. aureus at least partially determines atopic dermatitis (AtD) pathogenesis. AtD exacerbation is characterized by S. aureus growth activation and a decrease in microbial diversity. To assess the role of Staphylococcus spp. in AtD course in the pediatric population authors performed a study of skin colonization during disease exacerbation and in the period of symptoms remitting. Mean values on the SCORAD scale at the first and second visits were 60 (SD=23,3) and 40 points (SD=24,1) respectively (p<0,05). Frequency of affected skin colonization by S. aureus decreased from 85[%] during exacerbation to 27,5[%]. The prevalence of other coagulasenegative species and percentage of patients with sterile samples were also higher during AtD clinical improvement. So, AtD exacerbation was accompanied by affected skin colonization by S. aureus, clinical condition improvement by S. epidermidis growth activation and S. aureus growth suppression. Probably, being a representative of norma
Ключевые слова:
Atopic dermatitis; Children; Staphylococcus aureus; Staphylococcus epidermis
adolescent; Article; atopic dermatitis; bacterial colonization; child; disease exacerbation; growth inhibition; human; microbial diversity; microflora; nonhuman; pathogenesis; prevalence; skin defect; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis
Гележе Н. К. А. Нескородова К.А.
Кудрявцева А. В. Ася Валерьевна 1968-
Свитич О. А. Оксана Анатольевна 1979-
Gelezhe N. K. A. Neskorodova K.A.
Kudryavtseva A. V. Asya Valeryevna 1968-
Svitich O. A. Oksana Anatolyevna 1979-
Dynamics of skin colonization by staphylococcus spp. In children and adolescents with atopic dermatitis
Текст визуальный непосредственный
Педиатрия. Журнал им. Г.Н. Сперанского
ООО "Педиатрия"
Т. 98, Вып. 3 С. 88-93
2019
Статья
Atopic dermatitis Children Staphylococcus aureus Staphylococcus epidermis
adolescent Article atopic dermatitis bacterial colonization child disease exacerbation growth inhibition human microbial diversity microflora nonhuman pathogenesis prevalence skin defect Staphylococcus Staphylococcus aureus Staphylococcus epidermidis
Skin lesion with S. aureus at least partially determines atopic dermatitis (AtD) pathogenesis. AtD exacerbation is characterized by S. aureus growth activation and a decrease in microbial diversity. To assess the role of Staphylococcus spp. in AtD course in the pediatric population authors performed a study of skin colonization during disease exacerbation and in the period of symptoms remitting. Mean values on the SCORAD scale at the first and second visits were 60 (SD=23,3) and 40 points (SD=24,1) respectively (p<0,05). Frequency of affected skin colonization by S. aureus decreased from 85[%] during exacerbation to 27,5[%]. The prevalence of other coagulasenegative species and percentage of patients with sterile samples were also higher during AtD clinical improvement. So, AtD exacerbation was accompanied by affected skin colonization by S. aureus, clinical condition improvement by S. epidermidis growth activation and S. aureus growth suppression. Probably, being a representative of norma