Hemodynamic factors associated with fetal cardiac remodeling in late fetal growth restriction: A prospective study
Ritstso D., Mattioli C., Mappa I., Bitsadze V. O., Khizroeva D. Kh., Słodki M., Makatsarya A., D'Antonio F.
Journal of Perinatal Medicine
Vol.47, Issue7, P. 683-688
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1515/jpm-2019-0217
Аннотация:
Altered cardiac geometry affects a proportion of fetuses with growth restriction (FGR). The aim of this study was to explore the hemodynamic factors associated with cardiac remodeling in late FGR. This was a prospective study of singleton pregnancies complicated by late-onset FGR undergoing assessment of left (LV) and right (RV) ventricular sphericity-index (SI). The study population was divided in two groups according to the presence of cardiac remodelling, defined as LVSI <5th centile. The following outcomes were explored: Gestational age at birth, birthweight, caesarean section (CS) for fetal distress, umbilical artery (UA) pH and neonatal admission to special care unit. The differences between the 2 groups in UA pulsatility index (PI), middle cerebral artery (MCA) PI, uterine artery PI, cerebroplacental ratio (CPR) and umbilical vein (UV) flow corrected for fetal abdominal circumference (UVBF/AC) were tested. In total, 212 pregnancies with late FGR were enrolled in the study. An
Ключевые слова:
cardiac remodeling; late fetal growth restriction; sphericity index; umbilical vein flow
abdominal circumference; adult; Article; cardiovascular parameters; cerebroplacental ratio; cesarean section; controlled study; female; fetus distress; gestational age; heart hemodynamics; heart ventricle remodeling; hospital admission; human; intensive care unit; intrauterine growth retardation; late fetal growth restriction; left ventricular sphericity index; low birth weight; middle cerebral artery; middle cerebral artery pulsatility index; pH; placenta function; population research; priority journal; prospective study; pulsatility index; right ventricular sphericity index; umbilical artery; umbilical artery pH; umbilical vein; umbilical vein blood flow; vein blood flow; birth weight; complication; diagnostic imaging; Doppler ultrasonography; fetus distress; fetus echography; fetus heart; hemodynamics; intrauterine growth retardation; newborn; pathophysiology; pregnancy; procedures; small for date infant; third trimester pregnancy; umbilical vein; Adult; Birth Weight; Female; Fetal
Язык текста: Английский
ISSN: 1619-3997
Ritstso D. Dzhuzeppe 1958-
Mattioli C.
Mappa I.
Bitsadze V. O. Viktoriya Omarovna 1970-
Khizroeva D. Kh. Dzhamilya Khizrievna 1973-
Słodki M.
Makatsarya A.
D'Antonio F.
Риццо Д. Джузеппе 1958-
Маттиоли C.
Маппа И.
Бицадзе В. О. Виктория Омаровна 1970-
Хизроева Д. Х. Джамиля Хизриевна 1973-
Сłодки М.
Макацаря А.
Д'Антонио Ф.
Hemodynamic factors associated with fetal cardiac remodeling in late fetal growth restriction: A prospective study
Текст визуальный непосредственный
Journal of Perinatal Medicine
Walter de Gruyter GmbH
Vol.47, Issue7 P. 683-688
2019
Статья
cardiac remodeling late fetal growth restriction sphericity index umbilical vein flow
abdominal circumference adult Article cardiovascular parameters cerebroplacental ratio cesarean section controlled study female fetus distress gestational age heart hemodynamics heart ventricle remodeling hospital admission human intensive care unit intrauterine growth retardation late fetal growth restriction left ventricular sphericity index low birth weight middle cerebral artery middle cerebral artery pulsatility index pH placenta function population research priority journal prospective study pulsatility index right ventricular sphericity index umbilical artery umbilical artery pH umbilical vein umbilical vein blood flow vein blood flow birth weight complication diagnostic imaging Doppler ultrasonography fetus distress fetus echography fetus heart hemodynamics intrauterine growth retardation newborn pathophysiology pregnancy procedures small for date infant third trimester pregnancy umbilical vein Adult Birth Weight Female Fetal
Altered cardiac geometry affects a proportion of fetuses with growth restriction (FGR). The aim of this study was to explore the hemodynamic factors associated with cardiac remodeling in late FGR. This was a prospective study of singleton pregnancies complicated by late-onset FGR undergoing assessment of left (LV) and right (RV) ventricular sphericity-index (SI). The study population was divided in two groups according to the presence of cardiac remodelling, defined as LVSI <5th centile. The following outcomes were explored: Gestational age at birth, birthweight, caesarean section (CS) for fetal distress, umbilical artery (UA) pH and neonatal admission to special care unit. The differences between the 2 groups in UA pulsatility index (PI), middle cerebral artery (MCA) PI, uterine artery PI, cerebroplacental ratio (CPR) and umbilical vein (UV) flow corrected for fetal abdominal circumference (UVBF/AC) were tested. In total, 212 pregnancies with late FGR were enrolled in the study. An