Аннотация:
Abstract: To diagnose digestive diseases associated with Helicobacter pylori infection, we applied laser spectroscopic analysis of the 13СО2/12СО2 isotope ratio in the exhaled air, which is based on the use of tunable diode lasers. To analyze the isotopic composition of the exhaled air, we developed a spectrophotometer based on a tunable diode laser. The 13СО2/12СО2 ratio was determined using the spectral range near 2.05 μm, in which the R-branch of the 20013–00001 band of 12СО2 overlaps with the P-branch of the 20012–0001 band of 13СО2. H. pylori infection in the gastrointestinal tract of a group of 309 subjects was diagnosed using the 13C-urea breath test (13C-UBT). The breath test results were compared with the results of morphological analysis of the gastric and duodenal mucosa specimens obtained during fiber gastroduodenoscopy. To compare the results of laser 13C-UBT and histology, we have for the first time proposed to use the total values of the results of the histological analy
Ключевые слова:
Diagnosis; Diodes; Disease control; Isotopes; Laser spectroscopy; Pathology; Patient rehabilitation; Patient treatment; Semiconductor lasers; Urea; Gastrointestinal tract; Helicobacter pylori infections; Histological analysis; Inflammatory process; Isotopic composition; Laser spectroscopic analysis; Morphological analysis; Tunable diode lasers; Spectroscopic analysis
Ivashkin V. T. Vladimir Trofimovich 1939-
Kasoev S. G.
Stepanov E. V.
Ивашкин В. Т. Владимир Трофимович 1939-
Касоев С. Г.
Степанов Е. В.
Analysis of the Isotopic Composition of Exhaled Air by the Diode Laser Spectroscopy Method in the 2-μm Region for Diagnosis of Helicobacter pylori-Associated Diseases
Analysis of the Isotopic Composition of Exhaled Air by the Diode Laser Spectroscopy Method in the 2-μm Region for Diagnosis of Helicobacter...
Текст визуальный непосредственный
Optics and Spectroscopy
Pleiades Publishing, Ltd.
Vol.126, Issue6 P. 710-720
2019
Статья
Diagnosis Diodes Disease control Isotopes Laser spectroscopy Pathology Patient rehabilitation Patient treatment Semiconductor lasers Urea Gastrointestinal tract Helicobacter pylori infections Histological analysis Inflammatory process Isotopic composition Laser spectroscopic analysis Morphological analysis Tunable diode lasers Spectroscopic analysis
Abstract: To diagnose digestive diseases associated with Helicobacter pylori infection, we applied laser spectroscopic analysis of the 13СО2/12СО2 isotope ratio in the exhaled air, which is based on the use of tunable diode lasers. To analyze the isotopic composition of the exhaled air, we developed a spectrophotometer based on a tunable diode laser. The 13СО2/12СО2 ratio was determined using the spectral range near 2.05 μm, in which the R-branch of the 20013–00001 band of 12СО2 overlaps with the P-branch of the 20012–0001 band of 13СО2. H. pylori infection in the gastrointestinal tract of a group of 309 subjects was diagnosed using the 13C-urea breath test (13C-UBT). The breath test results were compared with the results of morphological analysis of the gastric and duodenal mucosa specimens obtained during fiber gastroduodenoscopy. To compare the results of laser 13C-UBT and histology, we have for the first time proposed to use the total values of the results of the histological analy