New antibacterial agents in the era of global drug resistance

Карева Е. Н., Сереброва С. Ю., Лазарева Н. Б., Шипилова С. Ю., Булгакова В. А., Козаева Л. П., Кононова И. Н., Яровои С. К., Дроздов В. Н., Стародубцев А. К.

Экспериментальная и клиническая фармакология

Т. 81, Вып. 9, С. 26-32

Опубликовано: 2018

Тип ресурса: Обзор

DOI:10.30906/0869-2092-2018-81-9-26-32

Аннотация:

The rise of resistance in bacteria, rendering pathogens unresponsive to many clinical drugs, is widely acknowledged and considered a critical global healthcare issue. This led to the emergence of bacterial infections which essentially do not lend themselves to treatment with the modern arsenal of available antibiotics. Various efforts have been made to develop new antimicrobial agents that can act against strains of drug-resistant pathogens. The article contains information on some new molecules approved since 2000, mechanisms of their action, the spectrum of antibacterial activity, and indications for use in relevant therapeutic regimens. © 2018 Izdatel'stvo Meditsina. All rights reserved.

Ключевые слова:

Antimicrobial agents; Drug-resistant pathogens; New molecules

antibiotic agent; antibacterial activity; antibiotic resistance; antibiotic therapy; bacterial infection; health care; Review

Язык текста: Русский

ISSN: 0869-2092

Карева Е. Н. Елена Николаевна 1961-

Сереброва С. Ю. Светлана Юрьевна 1971-

Лазарева Н. Б. Наталья Борисовна 1978-

Шипилова С. Ю. Светлана Юрьевна 1953-

Булгакова В. А. Виля Ахтямовна 1968-

Козаева Л. П. Лариса Петровна 1971-

Кононова И. Н.

Яровои С. К.

Дроздов В. Н. Владимир Николаевич 1963-

Стародубцев А. К. Алексей Константинович 1950-

Kareva E. N. Elena Nikolaevna 1961-

Serebrova S. Yu. Svetlana Yuryevna 1971-

Lazareva N. B. Natal`ya Borisovna 1978-

Shipilova S. Yu. Svetlana Yuryevna 1953-

Bulgakova V. A. Vilya Akhtyamovna 1968-

Kozaeva L. P. Larisa Petrovna 1971-

Kononova I. N.

Yarovoi S. K.

Drozdov V. N. Vladimir Nikolaevich 1963-

Starodubtsev A. K. Aleksej Konstantinovich 1950-

New antibacterial agents in the era of global drug resistance

Текст визуальный непосредственный

Экспериментальная и клиническая фармакология

ООО "Фолиум"

Т. 81, Вып. 9 С. 26-32

2018

Обзор

Antimicrobial agents Drug-resistant pathogens New molecules

antibiotic agent antibacterial activity antibiotic resistance antibiotic therapy bacterial infection health care Review

The rise of resistance in bacteria, rendering pathogens unresponsive to many clinical drugs, is widely acknowledged and considered a critical global healthcare issue. This led to the emergence of bacterial infections which essentially do not lend themselves to treatment with the modern arsenal of available antibiotics. Various efforts have been made to develop new antimicrobial agents that can act against strains of drug-resistant pathogens. The article contains information on some new molecules approved since 2000, mechanisms of their action, the spectrum of antibacterial activity, and indications for use in relevant therapeutic regimens. © 2018 Izdatel'stvo Meditsina. All rights reserved.