The gender features of disorders of composition of lipids of blood serum in patients with chronic pathology of kidneys
Муркамилов И. Т., Айтабаиев К. А., Фомин В. В., Муркамилова З. А., Райимйанов З. Р., Редйапова Н. А., Юсупов Ф. А., Айдаров З. А.
Клиническая лабораторная диагностика
Т. 63, Вып. 3, С. 152-158
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.18821/0869-2084-2018-63-3-152-158
Аннотация:
The purpose of the study was to investigate gender features of abnormalities of blood serum lipid composition and their relationship with clinical and functional manifestations in patients with chronic kidney disease (CKD). The study covered patients with CKD at pre-dialysis stage of disease, aged 17-71 years (average age 37.3±13.0 years). All patients underwent complex clinical and laboratory examination. Depending on gender, the sample (n = 417) was divided into 2 groups: group I - males (n = 277) and group II-females (n = 140). Blood sampling was implemented using venipuncture of ulnar vein after 12-14 hours of fasting in morning time. The lipid analysis of blood serum was performed using the auto-analyzer "Respons 920" (Germany), including detection of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG). The atherogenic index (AI) was calculated according formula: AI = (TC - HDL-C)/HDL-C. At analys
Ключевые слова:
Chronic kidney disease; Gender differences; Lipid profile
cholesterol; high density lipoprotein cholesterol; lipid; low density lipoprotein cholesterol; triacylglycerol; adolescent; adult; aged; blood; female; human; male; middle aged; young adult; Adolescent; Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Lipids; Male; Middle Aged; Triglycerides; Young Adult
Язык текста: Русский
ISSN: 0869-2084
Муркамилов И. Т.
Айтабаиев К. А.
Фомин В. В. Виктор Викторович 1978-
Муркамилова З. А. Ж.А.
Райимйанов З. Р.
Редйапова Н. А.
Юсупов Ф. А.
Айдаров З. А.
Murkamilov I. T.
Aytabaiev K. A.
Fomin V. V. Viktor Viktorovich 1978-
Murkamilova Z. A. Zh.A.
Rayimjanov Z. R.
Redjapova N. A.
Yusupov F. A.
Aydarov Z. A.
The gender features of disorders of composition of lipids of blood serum in patients with chronic pathology of kidneys
Текст визуальный непосредственный
Клиническая лабораторная диагностика
Издательство "Медицина"
Т. 63, Вып. 3 С. 152-158
2018
Статья
Chronic kidney disease Gender differences Lipid profile
cholesterol high density lipoprotein cholesterol lipid low density lipoprotein cholesterol triacylglycerol adolescent adult aged blood female human male middle aged young adult Adolescent Adult Aged Cholesterol Cholesterol, HDL Cholesterol, LDL Female Humans Lipids Male Middle Aged Triglycerides Young Adult
The purpose of the study was to investigate gender features of abnormalities of blood serum lipid composition and their relationship with clinical and functional manifestations in patients with chronic kidney disease (CKD). The study covered patients with CKD at pre-dialysis stage of disease, aged 17-71 years (average age 37.3±13.0 years). All patients underwent complex clinical and laboratory examination. Depending on gender, the sample (n = 417) was divided into 2 groups: group I - males (n = 277) and group II-females (n = 140). Blood sampling was implemented using venipuncture of ulnar vein after 12-14 hours of fasting in morning time. The lipid analysis of blood serum was performed using the auto-analyzer "Respons 920" (Germany), including detection of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG). The atherogenic index (AI) was calculated according formula: AI = (TC - HDL-C)/HDL-C. At analys