Germanium Dioxide and the Antioxidant Properties of Catechols
Nikolaevskaya E. N., Kansuzyan A. V., Filonova G. E., Zelenova V. A., Pechennikov V. M., Krylova I. V., Egorov M. P., Jouikov V. V., Syroeshkin M. A.
European Journal of Inorganic Chemistry
Vol.2019, Issue5, P. 676-681
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1002/ejic.201801259
Аннотация:
Complexes of tetra- and hexa-coordinated germanium AdrCat2Ge (1, AdrCat = adrenaline catecholate), AldCat2Ge (2, AldCat = 4-formylcatecholate), AldCat3Ge(Et3NH)2 (3) were synthesized by the reaction of germanium dioxide with adrenaline and 3,4-dihydroxybenzaldehyde in aqueous solution. The structures of the complexes were confirmed by 1H and 13C NMR and IR spectroscopy, HRMS, and elemental analysis. Cyclic voltammetry in phosphate buffer solutions (pH = 6.86) has shown the oxidation potentials Ep of these complexes to be shifted by ca. 330–360 mV to more positive potentials compared to the parent aromatic diols, which means that their electron-releasing properties were diminished by about 7.6–8.3 kcal mol–1. A study of the kinetics of the reaction of these complexes with 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical in the presence of 5 [%] acetonitrile reveals a decrease of approximately one order of magnitude in the radical scavenging activity of adrenaline and model 3,4-dihydroxyb
Ключевые слова:
Antioxidants; Germanium; Kinetics; Radical reactions; Redox chemistry
Язык текста: Английский
ISSN: 1099-0682
Nikolaevskaya E. N.
Kansuzyan A. V.
Filonova G. E. Galina Evgenyevna 1996-
Zelenova V. A. Vera Andreevna 1995-
Pechennikov V. M. Valerij Mikhaylovich 1943-
Krylova I. V.
Egorov M. P.
Jouikov V. V.
Syroeshkin M. A.
Николаевскайа Е. Н.
Кансузян А. В.
Филонова Г. Е. Галина Евгеньевна 1996-
Зеленова В. А. Вера Андреевна 1995-
Печенников В. М. Валерий Михайлович 1943-
Крyлова И. В.
Егоров М. П.
Йоуиков В. В.
Сyроешкин М. А.
Germanium Dioxide and the Antioxidant Properties of Catechols
Текст визуальный непосредственный
European Journal of Inorganic Chemistry
Wiley Interscience
Vol.2019, Issue5 P. 676-681
2019
Статья
Antioxidants Germanium Kinetics Radical reactions Redox chemistry
Complexes of tetra- and hexa-coordinated germanium AdrCat2Ge (1, AdrCat = adrenaline catecholate), AldCat2Ge (2, AldCat = 4-formylcatecholate), AldCat3Ge(Et3NH)2 (3) were synthesized by the reaction of germanium dioxide with adrenaline and 3,4-dihydroxybenzaldehyde in aqueous solution. The structures of the complexes were confirmed by 1H and 13C NMR and IR spectroscopy, HRMS, and elemental analysis. Cyclic voltammetry in phosphate buffer solutions (pH = 6.86) has shown the oxidation potentials Ep of these complexes to be shifted by ca. 330–360 mV to more positive potentials compared to the parent aromatic diols, which means that their electron-releasing properties were diminished by about 7.6–8.3 kcal mol–1. A study of the kinetics of the reaction of these complexes with 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical in the presence of 5 [%] acetonitrile reveals a decrease of approximately one order of magnitude in the radical scavenging activity of adrenaline and model 3,4-dihydroxyb