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A chronobiological approach to therapy for depression

Герасимчук М. Y.
Неврология, нейропсихиатрия, психосоматика
Т. 9, Вып. 3, С. 31-35
Опубликовано: 2017
Тип ресурса: Статья

DOI:10.14412/2074-2711-2017-3-31-35

Аннотация:
In the modern world, the discrepancy between biological and social rhythms in the presence of the existing genetic predisposition increases a risk for the occurrence and chronicity of depression. To solve this problem, various approaches, including a chronobiological one, are applied. Objective: to explore the relationship between chronobiological characteristics and psychopharmacotherapy in patients with depression. Patients and methods Eighty patients with depression, among whom women (68.7[%]) predominated, were examined. The age of the patients was 18-75 years (47.6±15.6 years). Their chronotype was identified using the Morningness-Eveningness Questionnaire (MEQ) to determine the type of circadian rhythm. Changes in the patients' status were clinically assessed utilizing the psychometric indicators. Results. Sleep disorders were most pronounced in recurrent depression (4.1±1.1 scores) (Montgomery-Asberg Depression Rating Scale, MADRS, item 4). The inverted pattern of daily variations
Ключевые слова:
Chronotype; Depression; MEQ; Psychopharmacotherapy; Sleep
Язык текста: Русский
ISSN: 2310-1342
Герасимчук М. Y. М.Ю.
Gerasimchuk M. Y. M.Yu.
A chronobiological approach to therapy for depression
Текст визуальный непосредственный
Неврология, нейропсихиатрия, психосоматика
ИМА-Пресс
Т. 9, Вып. 3 С. 31-35
2017
Статья
Chronotype Depression MEQ Psychopharmacotherapy Sleep
In the modern world, the discrepancy between biological and social rhythms in the presence of the existing genetic predisposition increases a risk for the occurrence and chronicity of depression. To solve this problem, various approaches, including a chronobiological one, are applied. Objective: to explore the relationship between chronobiological characteristics and psychopharmacotherapy in patients with depression. Patients and methods Eighty patients with depression, among whom women (68.7[%]) predominated, were examined. The age of the patients was 18-75 years (47.6±15.6 years). Their chronotype was identified using the Morningness-Eveningness Questionnaire (MEQ) to determine the type of circadian rhythm. Changes in the patients' status were clinically assessed utilizing the psychometric indicators. Results. Sleep disorders were most pronounced in recurrent depression (4.1±1.1 scores) (Montgomery-Asberg Depression Rating Scale, MADRS, item 4). The inverted pattern of daily variations