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Some peculiarities of acute myocardial infarction pathogenesis in non-obstructive coronary arteries

Dyatlov N. V., Ly'kov Yu. V., Zhelnov V. V., Dvoretskij L. I.
Медицинский вестник Северного Кавказа
Vol.12, Issue3, P. 260-265
Опубликовано: 2017
Тип ресурса: Статья

DOI:10.14300/mnnc.2017.12078

Аннотация:
Myocardial infarctions (MI) in case of non-obstructive atherosclerosis or intact coronary arteries are set apart into a separate group - myocardial infarction with no-obstructive coronary atherosclerosis - MINOCA. 1240 patients were included. The first group comprised the patients with single-vessel disease and complete acute occlusion -infarction of the responsible coronary artery (myocardial infarction with obstructive coronary atherosclerosis - MIOCA) 21.9 [%]. The second group comprised the patients with MINOCA 7.7 [%]. The average age of patients in Group 1 was 56.59±11.6 years, in Group 2 it amounted to 67.9±11.5 (p<0.001). Diabetes, CKD, exertional angina, symptoms of CHF and arterial hypertension were more likely for patients with MINOCA as compared to MIOCA - 20.8 [%] vs 7.4 [%] (p<0.05), 25.0 [%] vs 11.8 [%] (p<0.05), 29.2 [%] vs 14.7 [%] (p<0.05), 41.7 [%] vs 17.6 [%] (p<0.05) 91.7 [%] vs 72.1 [%] (p<0.01) respectively. Several mechanisms of myocardial necrosis were discussed: plaque disruption wit
Ключевые слова:
Intact coronary arteries; Myocardial infarction; Non-obstructive coronary atherosclerosis
Язык текста: Английский
ISSN: 2073-8137
Dyatlov N. V. Nikita Vyacheslavovich 1982-
Ly'kov Yu. V. Yurij Vladimirovich 1989-
Zhelnov V. V. Vladimir Vasilyevich 1941-
Dvoretskij L. I. Leonid Ivanovich 1940-
Дятлов Н. В. Никита Вячеславович 1982-
Лыков Ю. В. Юрий Владимирович 1989-
Желнов В. В. Владимир Васильевич 1941-
Дворецкий Л. И. Леонид Иванович 1940-
Some peculiarities of acute myocardial infarction pathogenesis in non-obstructive coronary arteries
Текст визуальный непосредственный
Медицинский вестник Северного Кавказа
Ставропольский государственный медицинский университет
Vol.12, Issue3 P. 260-265
2017
Статья
Intact coronary arteries Myocardial infarction Non-obstructive coronary atherosclerosis
Myocardial infarctions (MI) in case of non-obstructive atherosclerosis or intact coronary arteries are set apart into a separate group - myocardial infarction with no-obstructive coronary atherosclerosis - MINOCA. 1240 patients were included. The first group comprised the patients with single-vessel disease and complete acute occlusion -infarction of the responsible coronary artery (myocardial infarction with obstructive coronary atherosclerosis - MIOCA) 21.9 [%]. The second group comprised the patients with MINOCA 7.7 [%]. The average age of patients in Group 1 was 56.59±11.6 years, in Group 2 it amounted to 67.9±11.5 (p<0.001). Diabetes, CKD, exertional angina, symptoms of CHF and arterial hypertension were more likely for patients with MINOCA as compared to MIOCA - 20.8 [%] vs 7.4 [%] (p<0.05), 25.0 [%] vs 11.8 [%] (p<0.05), 29.2 [%] vs 14.7 [%] (p<0.05), 41.7 [%] vs 17.6 [%] (p<0.05) 91.7 [%] vs 72.1 [%] (p<0.01) respectively. Several mechanisms of myocardial necrosis were discussed: plaque disruption wit