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Endothelial dysfunction and arterial wall stiffness: New targets in diabetic nephropathy

Муркамилов И. Т., Сабиров И. С., Фомин В. В., Юсупов Ф. А.
Терапевтический архив
Т. 89, Вып. 10, С. 87-94
Опубликовано: 2017
Тип ресурса: Обзор

DOI:10.17116/terarkh2017891087-94

Аннотация:
In recent years, one of the promising areas in clinical medicine is the study of impaired ments in endothelial function and arterial wall stiffness, which can be referred to as one of the important predictors of cardiovascular events in patients with chronic kidney disease, including that of diabetic etiology. There is strong evidence that endothelial function and great artery stiffness may be used as reliable clinical and instrumental indicators to evaluate the efficiency of therapeutic measures and the rate of progression of cardiovascular disorders in type 2 diabetes mellitus. The article presents data on the role of endothelial dysfunction and arterial wall stiffness in the progression of chronic kidney disease in type 2 diabetes mellitus and discusses the possibility of their correction with pharmacological agents.
Ключевые слова:
Arterial wall stiffness; Cardiovascular diseases; Chronic kidney disease; Diabetes mellitus; Endothelial dysfunction
protective agent; arterial stiffness; complication; diabetic nephropathy; disease exacerbation; drug effects; human; non insulin dependent diabetes mellitus; pathophysiology; prognosis; vascular endothelium; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Endothelium, Vascular; Humans; Prognosis; Protective Agents; Vascular Stiffness
Язык текста: Русский
ISSN: 2309-5342
Муркамилов И. Т.
Сабиров И. С.
Фомин В. В. Виктор Викторович 1978-
Юсупов Ф. А.
Murkamilov I. T.
Sabirov I. S.
Fomin V. V. Viktor Viktorovich 1978-
Yusupov F. A.
Endothelial dysfunction and arterial wall stiffness: New targets in diabetic nephropathy
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 89, Вып. 10 С. 87-94
2017
Обзор
Arterial wall stiffness Cardiovascular diseases Chronic kidney disease Diabetes mellitus Endothelial dysfunction
protective agent arterial stiffness complication diabetic nephropathy disease exacerbation drug effects human non insulin dependent diabetes mellitus pathophysiology prognosis vascular endothelium Diabetes Mellitus, Type 2 Diabetic Nephropathies Disease Progression Endothelium, Vascular Humans Prognosis Protective Agents Vascular Stiffness
In recent years, one of the promising areas in clinical medicine is the study of impaired ments in endothelial function and arterial wall stiffness, which can be referred to as one of the important predictors of cardiovascular events in patients with chronic kidney disease, including that of diabetic etiology. There is strong evidence that endothelial function and great artery stiffness may be used as reliable clinical and instrumental indicators to evaluate the efficiency of therapeutic measures and the rate of progression of cardiovascular disorders in type 2 diabetes mellitus. The article presents data on the role of endothelial dysfunction and arterial wall stiffness in the progression of chronic kidney disease in type 2 diabetes mellitus and discusses the possibility of their correction with pharmacological agents.