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The possibilities for the restoration of the laryngeal function: The current state-of-the-Art

Решетов И. В., Полунин Г. В., Ананичук А. В., Ипполитов Л. И., Коваленко А. А.
Вестник оториноларингологии
Т. 82, Вып. 6, С. 18-23
Опубликовано: 2017
Тип ресурса: Статья

DOI:10.17116/otorino201782618-23

Аннотация:
The restoration of the functional competence of the larynx following bilateral laryngeal nerve damage and vocal fold paralysis is a serious challenge for the surgeon that has thus far no satisfactory solution. Physiological re-innervation that occurs naturally with time is non-selective and, in the majority of the cases, leads to synkinesis. Laryngeal pacing achieved with the application of the implantable microchips appears to be a promising approach. The animal experiments have demonstrated the possibility of successful restoration of all the functions of the larynx by means of laryngeal pacing but simultaneously revealed a number of technical issues that have to be addressed if the further progress in this field is to be achieved including the choice of the proper materials for implantation, solution of problems pertaining to the neuromuscular mapping during pacer implantation, etc.). The results of the first prospective clinical trial involving the human patients gave evidence sugg
Ключевые слова:
Implantable electrostimlators; Laryngeal electrostimlation; Laryngeal pacing; Laryngeal palsy
convalescence; devices; electrode implant; electrostimulation; human; invention; laryngeal nerve injury; pathology; pathophysiology; procedures; recurrent laryngeal nerve; vocal cord paralysis; Electric Stimulation; Electrodes, Implanted; Humans; Inventions; Laryngeal Nerve Injuries; Recovery of Function; Recurrent Laryngeal Nerve; Vocal Cord Paralysis
Язык текста: Русский
ISSN: 2309-1274
Решетов И. В. Игорь Владимирович 1964-
Полунин Г. В. Георгий Владимирович 1977-
Ананичук А. В. Анна Викторовна 1992-
Ипполитов Л. И. Леонид Игоревич 1966-
Коваленко А. А.
Reshetov I. V. Igor` Vladimirovich 1964-
Polunin G. V. Georgij Vladimirovich 1977-
Ananichuk A. V. Anna Viktorovna 1992-
Ippolitov L. I. Leonid Igorevich 1966-
Kovalenko A. A.
The possibilities for the restoration of the laryngeal function: The current state-of-the-Art
Текст визуальный непосредственный
Вестник оториноларингологии
Издательство Медиа Сфера
Т. 82, Вып. 6 С. 18-23
2017
Статья
Implantable electrostimlators Laryngeal electrostimlation Laryngeal pacing Laryngeal palsy
convalescence devices electrode implant electrostimulation human invention laryngeal nerve injury pathology pathophysiology procedures recurrent laryngeal nerve vocal cord paralysis Electric Stimulation Electrodes, Implanted Humans Inventions Laryngeal Nerve Injuries Recovery of Function Recurrent Laryngeal Nerve Vocal Cord Paralysis
The restoration of the functional competence of the larynx following bilateral laryngeal nerve damage and vocal fold paralysis is a serious challenge for the surgeon that has thus far no satisfactory solution. Physiological re-innervation that occurs naturally with time is non-selective and, in the majority of the cases, leads to synkinesis. Laryngeal pacing achieved with the application of the implantable microchips appears to be a promising approach. The animal experiments have demonstrated the possibility of successful restoration of all the functions of the larynx by means of laryngeal pacing but simultaneously revealed a number of technical issues that have to be addressed if the further progress in this field is to be achieved including the choice of the proper materials for implantation, solution of problems pertaining to the neuromuscular mapping during pacer implantation, etc.). The results of the first prospective clinical trial involving the human patients gave evidence sugg