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The radical-producing function of neutrophils in habitual miscarriage: The use of the method of activated chemiluminescence with double stimulation

Покаленьева М. С., Нестерова А. М., Соснова Е. А., Болевич С., Проскурнина Е. В.
Вопросы гинекологии, акушерства и перинатологии
Т. 16, Вып. 5, С. 82-88
Опубликовано: 2017
Тип ресурса: Статья

DOI:10.20953/1726-1678-2017-5-82-88

Аннотация:
The objective. To study the radical producing function of phagocytes in women with habitual miscarriage (HM) using a new method of activated chemiluminescence with double consecutive stimulation. To specify possible diagnostic and prognostic parameters. Patients and methods. The study included 28 pregnant women with threatened miscarriage (TM), of whom 19 were diagnosed with habitual miscarriage, 9 women with non-developing pregnancy (NP). Control group 1 (C1) comprised 61 women with the normal course of pregnancy. Control group 2 (C2) - 24 nonpregnant women, 5 women after spontaneous abortion before 22 wks. (C3). Results. During pregnancy, both physiological and occurring against the background of threatened miscarriage, neutrophils are in the primed state. In the group of patients after spontaneous abortion, an enhanced activity of the neutrophil link of the immune system was noted before and immediately after miscarriage, on the contrary, in women with NP response to stimuli was wea
Ключевые слова:
Activated neutrophils; Active oxygen forms; Habitual miscarriage; Oxidative stress
Язык текста: Русский
ISSN: 2414-9152
Покаленьева М. С.
Нестерова А. М.
Соснова Е. А. Елена Алексеевна 1957-
Болевич С. Сергей 1964-
Проскурнина Е. В.
Pokalenyeva M. S.
Nesterova A. M.
Sosnova E. A. Elena Alekseevna 1957-
Bolevich S. Sergej 1964-
Proskurnina E. V.
The radical-producing function of neutrophils in habitual miscarriage: The use of the method of activated chemiluminescence with double stimulation
Текст визуальный непосредственный
Вопросы гинекологии, акушерства и перинатологии
ООО "Издательство "Династия"
Т. 16, Вып. 5 С. 82-88
2017
Статья
Activated neutrophils Active oxygen forms Habitual miscarriage Oxidative stress
The objective. To study the radical producing function of phagocytes in women with habitual miscarriage (HM) using a new method of activated chemiluminescence with double consecutive stimulation. To specify possible diagnostic and prognostic parameters. Patients and methods. The study included 28 pregnant women with threatened miscarriage (TM), of whom 19 were diagnosed with habitual miscarriage, 9 women with non-developing pregnancy (NP). Control group 1 (C1) comprised 61 women with the normal course of pregnancy. Control group 2 (C2) - 24 nonpregnant women, 5 women after spontaneous abortion before 22 wks. (C3). Results. During pregnancy, both physiological and occurring against the background of threatened miscarriage, neutrophils are in the primed state. In the group of patients after spontaneous abortion, an enhanced activity of the neutrophil link of the immune system was noted before and immediately after miscarriage, on the contrary, in women with NP response to stimuli was wea