Вопросы современной педиатрии
Т. 17, Вып. 2, С. 166-169
Аннотация:
The article discusses issues related to the long-term administration of macrolide antibiotics for a bronchoectatic disorder of the pulmonary system in children. The relevant information about the results of long-term intake of macrolides in adults and children, the effective dose titration, possible toxic effects of therapy, including the development of cardiotoxic effect and ways to prevent it, has been enlightened in detail. It has been noted that a limited number of clinical studies involving children determine the need for studying the possibility to extrapolate adult treatment. © 2018 Publishing House of the Union of Pediatricians. All rights reserved.
Ключевые слова:
Bronchiectases; Children; Chronic diseases of the lower respiratory tract; Macrolides
macrolide; Article; bronchiectasis; cardiotoxicity; child; drug efficacy; drug use; human; outcome assessment; treatment duration
Лазарева Н. Б. Наталья Борисовна 1978-
Ших Е. В. Евгения Валерьевна 1962-
Реброва Е. В. Екатерина Владиславовна 1987-
Lazareva N. B. Natal`ya Borisovna 1978-
Shikh E. V. Evgeniya Valeryevna 1962-
Rebrova E. V. Ekaterina Vladislavovna 1987-
Outcomes of the long-term administration of macrolide antibiotics in children with bronchiectases: Frequently asked questions
Текст визуальный непосредственный
Вопросы современной педиатрии
Издательство "Педиатръ"
Т. 17, Вып. 2 С. 166-169
2018
Статья
Bronchiectases Children Chronic diseases of the lower respiratory tract Macrolides
macrolide Article bronchiectasis cardiotoxicity child drug efficacy drug use human outcome assessment treatment duration
The article discusses issues related to the long-term administration of macrolide antibiotics for a bronchoectatic disorder of the pulmonary system in children. The relevant information about the results of long-term intake of macrolides in adults and children, the effective dose titration, possible toxic effects of therapy, including the development of cardiotoxic effect and ways to prevent it, has been enlightened in detail. It has been noted that a limited number of clinical studies involving children determine the need for studying the possibility to extrapolate adult treatment. © 2018 Publishing House of the Union of Pediatricians. All rights reserved.