Calcium phosphate composite cements based on simple mixture of brushite and apatite phases
Egorov A. A., Fedotov A. Y., Pereloma I. S., Teterina A. Y., Sergeeva N. S., Sviridova I. K., Kirsanova V. A., Akhmedova S. A., Nesterova A. V., Reshetov I. V., Barinov S. M., Komlev V. S.
IOP Conference Series: Materials Science and Engineering
Vol.347, Issue1, Num.012039
Опубликовано: 2018
Тип ресурса: Материалы конференции (Статья)
DOI:10.1088/1757-899X/347/1/012039
Аннотация:
The composite cements based on simple mixtures brishite and apatite with ratio 70/30, 50/50, 30/70 were developed. The processes of phase formation, microstructure and mechanical properties were studied. The kinetics of degradation in simulated body fluid depending on the microstructure and the materials phase composition was carried out. The biological test in vitro were performed using the MTT-test on the human fibroblast immortalized (hFB) cell line and the human osteosarcoma cell line MG-63. The materials didn't have acute cytoxicity and possessed surface matrix properties. It was determined that the both line of cells actively proliferated, with viable cells values higher 20-60 [%] then control at all observation periods. © 2018 Institute of Physics Publishing. All rights reserved.
Ключевые слова:
Apatite; Calcium phosphate; Cell culture; Cells; Cements; Microstructure; Mixtures; Biological tests; Composite cements; Human fibroblast; Human osteosarcoma cells; Kinetics of degradation; Microstructure and mechanical properties; Observation Period; Simulated body fluids; Biomechanics
Язык текста: Английский
ISSN: 1757-899X
Egorov A. A.
Fedotov A. Y.
Pereloma I. S.
Teterina A. Y.
Sergeeva N. S.
Sviridova I. K.
Kirsanova V. A.
Akhmedova S. A.
Nesterova A. V.
Reshetov I. V. Igor` Vladimirovich 1964-
Barinov S. M.
Komlev V. S.
Егоров А. А.
Федотов А. Y.
Перелома И. С.
Тетерина А. Y.
Сергеева Н. С.
Свиридова И. К.
Кирсанова В. А.
Ахмедова С. А.
Нестерова А. В.
Решетов И. В. Игорь Владимирович 1964-
Баринов С. М.
Комлев В. С.
Calcium phosphate composite cements based on simple mixture of brushite and apatite phases
Текст визуальный непосредственный
IOP Conference Series: Materials Science and Engineering
Vol.347, Issue1 Num.012039
2018
Материалы конференции (Статья)
Apatite Calcium phosphate Cell culture Cells Cements Microstructure Mixtures Biological tests Composite cements Human fibroblast Human osteosarcoma cells Kinetics of degradation Microstructure and mechanical properties Observation Period Simulated body fluids Biomechanics
The composite cements based on simple mixtures brishite and apatite with ratio 70/30, 50/50, 30/70 were developed. The processes of phase formation, microstructure and mechanical properties were studied. The kinetics of degradation in simulated body fluid depending on the microstructure and the materials phase composition was carried out. The biological test in vitro were performed using the MTT-test on the human fibroblast immortalized (hFB) cell line and the human osteosarcoma cell line MG-63. The materials didn't have acute cytoxicity and possessed surface matrix properties. It was determined that the both line of cells actively proliferated, with viable cells values higher 20-60 [%] then control at all observation periods. © 2018 Institute of Physics Publishing. All rights reserved.