3D printing biodegradable scaffolds with chitosan materials for tissue engineering
Bardakova K. N., Demina T. S., Ivukina E. A., Minaev N. V., Akopova T. A., Bagratashvili V. N., Timashev P. S.
IOP Conference Series: Materials Science and Engineering
Vol.347, Issue1, Num.012009
Опубликовано: 2018
Тип ресурса: Материалы конференции (Статья)
DOI:10.1088/1757-899X/347/1/012009
Аннотация:
Chitosan-g-oligo (L,L-lactide) copolymer was synthesized through a solvent-free reaction in an extruder. Three-dimensional scaffolds based on photosensitive composition contained the synthetized copolymer were formed by two-photon polymerization. The optimum ratio of components, methods of preparation of photopolymerizable mixtures, parameters of the laser structuring and procedure of washing from unbound crosslinkers have been optimized. Chitosan scaffolds were non-cytotoxic and might therefore be a suitable candidate for treating spinal cord injuries and other neuronal degenerative diseases. © 2018 Institute of Physics Publishing. All rights reserved.
Ключевые слова:
3D printers; Chitosan; Biodegradable scaffold; Chitosan materials; Chitosan scaffold; Degenerative disease; Solvent free reaction; Spinal cord injuries (SCI); Three dimensional scaffold; Two photon polymerization; Scaffolds (biology)
Язык текста: Английский
ISSN: 1757-899X
Bardakova K. N. Kseniya Nikolaevna 1993-
Demina T. S. Tat`yana Sergeevna 1986-
Ivukina E. A. Ekaterina Andreevna 1986-
Minaev N. V.
Akopova T. A.
Bagratashvili V. N.
Timashev P. S. Petr Sergeevich 1978-
Бардакова К. Н. Ксения Николаевна 1993-
Демина Т. С. Татьяна Сергеевна 1986-
Ивукина Е. А. Екатерина Андреевна 1986-
Минаев Н. В.
Акопова Т. А.
Баграташвили В. Н.
Тимашев П. С. Петр Сергеевич 1978-
3D printing biodegradable scaffolds with chitosan materials for tissue engineering
Текст визуальный непосредственный
IOP Conference Series: Materials Science and Engineering
Vol.347, Issue1 Num.012009
2018
Материалы конференции (Статья)
3D printers Chitosan Biodegradable scaffold Chitosan materials Chitosan scaffold Degenerative disease Solvent free reaction Spinal cord injuries (SCI) Three dimensional scaffold Two photon polymerization Scaffolds (biology)
Chitosan-g-oligo (L,L-lactide) copolymer was synthesized through a solvent-free reaction in an extruder. Three-dimensional scaffolds based on photosensitive composition contained the synthetized copolymer were formed by two-photon polymerization. The optimum ratio of components, methods of preparation of photopolymerizable mixtures, parameters of the laser structuring and procedure of washing from unbound crosslinkers have been optimized. Chitosan scaffolds were non-cytotoxic and might therefore be a suitable candidate for treating spinal cord injuries and other neuronal degenerative diseases. © 2018 Institute of Physics Publishing. All rights reserved.