A case of vaccine-associated paralytic poliomyelitis in an infant
Шишов А. С., Иванова О. Е., Шакарян А. К., Козловская Л. И., Митропханова И. В., Шачгилдян С. В.
Журнал неврологии и психиатрии им. C.C. Корсакова
Т. 118, Вып. 4, С. 84-89
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.17116/jnevro20181184184-89
Аннотация:
Objective. To present the clinical history, vaccination status, features of the clinical picture, composition of the cerebrospinal fluid (CSF), results of laboratory and instrumental examinations of a patient with vaccine-associated paralytic poliomyelitis (VAPP). Material and methods. In 2017, a child, aged 15 month, mistakenly vaccinated with the first dose of bivalent (types 1 & 3) polioviruses oral vaccine (OPV) was followed up. Results and conclusion. Clinical parameters of VAPP in the recipient of OPV are considered. Clinical features of disease caused by wild poliovirus and VAPP are compared. The disease was characterized by sudden onset, recurrence, short (2—4 days) period of progression of paresis, persistent residual effects, CSF protein-cell dissociation. It is emphasized that the occurrence of VAPP cases reflects primarily immunization defects. © 2018, Media Sphera Publishing Group. All Rights Reserved.
Ключевые слова:
Cerebrospinal fluid; Clinical picture; Vaccine associated paralytic poliomyelitis; Virological examination
oral poliomyelitis vaccine; poliomyelitis vaccine; Article; case report; cerebrospinal fluid cytology; child; clinical article; clinical assessment; disease exacerbation; follow up; human; immunization; paralytic poliomyelitis; paresis; Poliomyelitis virus; preschool child; protein cerebrospinal fluid level; recurrent disease; relapse; chemically induced; infant; poliomyelitis; Poliomyelitis virus; Humans; Infant; Paresis; Poliomyelitis; Poliovirus; Poliovirus Vaccines
Язык текста: Русский
ISSN: 2309-4729
Шишов А. С.
Иванова О. Е. Ольга Евгеньевна 1955-
Шакарян А. К.
Козловская Л. И. Любовь Игоревна 1984-
Митропханова И. В.
Шачгилдян С. В.
Shishov A. S.
Ivanova O. E. Ol`ga Evgenyevna 1955-
Shakaryan A. K.
Kozlovskaya L. I. Lyubov` Igorevna 1984-
Mitrophanova I. V.
Shachgildyan S. V.
A case of vaccine-associated paralytic poliomyelitis in an infant
Текст визуальный непосредственный
Журнал неврологии и психиатрии им. C.C. Корсакова
Издательство Медиа Сфера
Т. 118, Вып. 4 С. 84-89
2018
Статья
Cerebrospinal fluid Clinical picture Vaccine associated paralytic poliomyelitis Virological examination
oral poliomyelitis vaccine poliomyelitis vaccine Article case report cerebrospinal fluid cytology child clinical article clinical assessment disease exacerbation follow up human immunization paralytic poliomyelitis paresis Poliomyelitis virus preschool child protein cerebrospinal fluid level recurrent disease relapse chemically induced infant poliomyelitis Poliomyelitis virus Humans Infant Paresis Poliomyelitis Poliovirus Poliovirus Vaccines
Objective. To present the clinical history, vaccination status, features of the clinical picture, composition of the cerebrospinal fluid (CSF), results of laboratory and instrumental examinations of a patient with vaccine-associated paralytic poliomyelitis (VAPP). Material and methods. In 2017, a child, aged 15 month, mistakenly vaccinated with the first dose of bivalent (types 1 & 3) polioviruses oral vaccine (OPV) was followed up. Results and conclusion. Clinical parameters of VAPP in the recipient of OPV are considered. Clinical features of disease caused by wild poliovirus and VAPP are compared. The disease was characterized by sudden onset, recurrence, short (2—4 days) period of progression of paresis, persistent residual effects, CSF protein-cell dissociation. It is emphasized that the occurrence of VAPP cases reflects primarily immunization defects. © 2018, Media Sphera Publishing Group. All Rights Reserved.