Аннотация:
Aims: To evaluate safety and efficacy of moderate intensity interval exercise training early after heart failure decompensation on exercise tolerance and health-related quality of life (HRQoL). Methods and results: This is a prospective randomized controlled study. We screened 234 consecutive patients admitted with decompensated heart failure; 46 patients (42 men/4 women; 61±12 years of age) were randomized to a moderate intensity aerobic interval training (n = 24) or to a control group (n = 22). Patients underwent cardiopulmonary exercise testing, echocardiography and Minnesota Living with Heart Failure questionnaire (MLHFQ) at baseline, after three weeks and after three months. After three weeks, peak-VO2 increased by 17[%] in the training group (p = 0.003) with further increase by 10[%] after three months (p < 0.001) but did not change significantly in controls. MLHFQ score improved after three weeks, with better results in the training group (from 64.6±15.6 to 30.8±12.9, p < 0.00
Doletsky A.
Andreev D. A. Denis Anatolyevich 1968-
Giverts I. Yu. Il`ya Yuryevich 1982-
Svet A. V. Aleksej Viktorovich 1969-
Brand A. V. Anna Vladimirovna 1982-
Kuklina M.
Sedov V. P. Vsevolod Parisovich 1952-
Dikur O. N. Oksana Nikolaevna 1987-
Sy'rkin A. L. Abram L`vovich 1930-
Saner Kh. E`. Khugo E`rnst 1948-
Долецкy А.
Андреев Д. А. Денис Анатольевич 1968-
Гиверц И. Ю. Илья Юрьевич 1982-
Свет А. В. Алексей Викторович 1969-
Бранд А. В. Анна Владимировна 1982-
Куклина М.
Седов В. П. Всеволод Парисович 1952-
Дикур О. Н. Оксана Николаевна 1987-
Сыркин А. Л. Абрам Львович 1930-
Санер Х. Э. Хуго Эрнст 1948-
Interval training early after heart failure decompensation is safe and improves exercise tolerance and quality of life in selected patients
Текст визуальный непосредственный
European Journal of Preventive Cardiology
Vol.25, Issue1 P. 9-18
2018
Статья
Exercise tolerance Exercise training Heart failure Interval training Quality of life
amiodarone beta adrenergic receptor blocking agent digoxin dipeptidyl carboxypeptidase inhibitor furosemide loop diuretic agent adult aerobic exercise aged Article cardiopulmonary exercise test controlled study drug dose titration dyspnea echocardiography exercise tolerance fatigue female follow up heart failure heart left ventricle ejection fraction heart left ventricle enddiastolic volume heart left ventricle endsystolic volume heart rate hospitalization human hypotension lung gas exchange major clinical study male Minnesota Living with Heart Failure questionnaire moderate intensity interval exercise training myalgia oxygen consumption paroxysmal atrial fibrillation patient safety priority journal program efficacy prospective study quality of life questionnaire randomized controlled trial recommended drug dose single blind procedure six minute walk test training convalescence exercise exercise test heart failure heart rehabilitation
Aims: To evaluate safety and efficacy of moderate intensity interval exercise training early after heart failure decompensation on exercise tolerance and health-related quality of life (HRQoL). Methods and results: This is a prospective randomized controlled study. We screened 234 consecutive patients admitted with decompensated heart failure; 46 patients (42 men/4 women; 61±12 years of age) were randomized to a moderate intensity aerobic interval training (n = 24) or to a control group (n = 22). Patients underwent cardiopulmonary exercise testing, echocardiography and Minnesota Living with Heart Failure questionnaire (MLHFQ) at baseline, after three weeks and after three months. After three weeks, peak-VO2 increased by 17[%] in the training group (p = 0.003) with further increase by 10[%] after three months (p < 0.001) but did not change significantly in controls. MLHFQ score improved after three weeks, with better results in the training group (from 64.6±15.6 to 30.8±12.9, p < 0.00