The use of growth factors in periodontitis treatment
Мудров В. П., Нелюбин В. Н., Воробиева Е. С., Лyсиук Е. Y., Мяндиев М. С., Фоменков И. С., Иванов С. Ю.
Медицинская иммунология
Т. 20, Вып. 3, С. 439-444
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.15789/1563-0625-2018-3-439-444
Аннотация:
Periodontal disease, including gum disease, gingivitis, periodontitis and periodontal disease is frequently associated with progressive loss of bone and soft periodontal tissues. Recent studies suggest effectiveness of platelet-derived growth factor, fibroblast growth factor and other growth factors, which may stimulate regeneration of connective and bone tissue. A number of cytokines and growth factors participate in regulation of angiogenesis, but vascular endothelial growth factor (VEGF) is the most powerful agent, acting directly on the vascular endothelium. VEGF detected in saliva and endothelial cells of periodontium. VEGF plays a dominant role both in periodontal health maintenance as well as in chronic inflammatory periodontal disease. The aim of this work was to develop implementation of VEGF in periodontology, and a search for laboratory markers of therapeutic efficiency in periodontitis. We observed 19 patients aged 53-79 years with I-II grade periodontitis. In frames of per
Ключевые слова:
Cytokines; Dento-gingival fluid; Growth factors; IFNγ; Periodontitis; VEGF
Язык текста: Русский
ISSN: 2313-741X
Мудров В. П.
Нелюбин В. Н.
Воробиева Е. С.
Лyсиук Е. Y. Е.Ю.
Мяндиев М. С. Морис Садикович 1988-
Фоменков И. С. Илья Сергеевич 1986-
Иванов С. Ю. Сергей Юрьевич 1957-
Mudrov V. P.
Nelyubin V. N.
Vorobieva E. S.
Lysiuk E. Y. E.Yu.
Myandiev M. S. Moris Sadikovich 1988-
Fomenkov I. S. Il`ya Sergeevich 1986-
Ivanov S. Yu. Sergej Yuryevich 1957-
The use of growth factors in periodontitis treatment
Текст визуальный непосредственный
Медицинская иммунология
Санкт-Петербургское региональное отделение Российской ассоциации аллергологов и клинических иммунологов
Т. 20, Вып. 3 С. 439-444
2018
Статья
Cytokines Dento-gingival fluid Growth factors IFNγ Periodontitis VEGF
Periodontal disease, including gum disease, gingivitis, periodontitis and periodontal disease is frequently associated with progressive loss of bone and soft periodontal tissues. Recent studies suggest effectiveness of platelet-derived growth factor, fibroblast growth factor and other growth factors, which may stimulate regeneration of connective and bone tissue. A number of cytokines and growth factors participate in regulation of angiogenesis, but vascular endothelial growth factor (VEGF) is the most powerful agent, acting directly on the vascular endothelium. VEGF detected in saliva and endothelial cells of periodontium. VEGF plays a dominant role both in periodontal health maintenance as well as in chronic inflammatory periodontal disease. The aim of this work was to develop implementation of VEGF in periodontology, and a search for laboratory markers of therapeutic efficiency in periodontitis. We observed 19 patients aged 53-79 years with I-II grade periodontitis. In frames of per