Farming, slaving and enslavement: Histories of endosymbioses during kinetoplastid evolution
Harmer J., Yurchenko V., Nenarokova A., Lukeš J., Ginger M. L.
Parasitology
Vol.145, Issue10, P. 1311-1323
Опубликовано: 2018
Тип ресурса: Обзор
DOI:10.1017/S0031182018000781
Аннотация:
Parasitic trypanosomatids diverged from free-living kinetoplastid ancestors several hundred million years ago. These parasites are relatively well known, due in part to several unusual cell biological and molecular traits and in part to the significance of a few -pathogenic Leishmania and Trypanosoma species -as aetiological agents of serious neglected tropical diseases. However, the majority of trypanosomatid biodiversity is represented by osmotrophic monoxenous parasites of insects. In two lineages, novymonads and strigomonads, osmotrophic lifestyles are supported by cytoplasmic endosymbionts, providing hosts with macromolecular precursors and vitamins. Here we discuss the two independent origins of endosymbiosis within trypanosomatids and subsequently different evolutionary trajectories that see entrainment vs tolerance of symbiont cell divisions cycles within those of the host. With the potential to inform on the transition to obligate parasitism in the trypanosomatids, interest in
Ключевые слова:
Angomonas deanei; Candidatus Kinetoplastibacterium; cytostome; Kentomonas; Novymonas esmeraldas; Pandoraea
vitamin; biodiversity; cell division; endosymbiont; endosymbiosis; host cell; Kinetoplastida; nonhuman; parasitism; Perkinsela; phagotroph; priority journal; Review; symbiont; Trypanosomatidae; evolution; genetics; genome; Kinetoplastida; Leishmania; molecular evolution; physiology; symbiosis; Trypanosoma; Biodiversity; Biological Evolution; Evolution, Molecular; Genome, Protozoan; Kinetoplastida; Leishmania; Symbiosis; Trypanosoma; Trypanosomatina
Язык текста: Английский
ISSN: 1469-8161
Harmer J.
Yurchenko V. Vyacheslav 1972-
Nenarokova A.
Lukeš J.
Ginger M. L.
Хармер Й.
Юрченко В. Вячеслав 1972-
Ненарокова А.
Лукеš Й.
Гингер М. Л.
Farming, slaving and enslavement: Histories of endosymbioses during kinetoplastid evolution
Текст визуальный непосредственный
Parasitology
Cambridge University Press
Vol.145, Issue10 P. 1311-1323
2018
Обзор
Angomonas deanei Candidatus Kinetoplastibacterium cytostome Kentomonas Novymonas esmeraldas Pandoraea
vitamin biodiversity cell division endosymbiont endosymbiosis host cell Kinetoplastida nonhuman parasitism Perkinsela phagotroph priority journal Review symbiont Trypanosomatidae evolution genetics genome Kinetoplastida Leishmania molecular evolution physiology symbiosis Trypanosoma Biodiversity Biological Evolution Evolution, Molecular Genome, Protozoan Kinetoplastida Leishmania Symbiosis Trypanosoma Trypanosomatina
Parasitic trypanosomatids diverged from free-living kinetoplastid ancestors several hundred million years ago. These parasites are relatively well known, due in part to several unusual cell biological and molecular traits and in part to the significance of a few -pathogenic Leishmania and Trypanosoma species -as aetiological agents of serious neglected tropical diseases. However, the majority of trypanosomatid biodiversity is represented by osmotrophic monoxenous parasites of insects. In two lineages, novymonads and strigomonads, osmotrophic lifestyles are supported by cytoplasmic endosymbionts, providing hosts with macromolecular precursors and vitamins. Here we discuss the two independent origins of endosymbiosis within trypanosomatids and subsequently different evolutionary trajectories that see entrainment vs tolerance of symbiont cell divisions cycles within those of the host. With the potential to inform on the transition to obligate parasitism in the trypanosomatids, interest in