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Non-motor disorders in patients with muscular dystonia

Салоучина Н. И., Нодель М. Р., Толмачева В. А.
Журнал неврологии и психиатрии им. C.C. Корсакова
Т. 118, Вып. 9, С. 98-105
Опубликовано: 2018
Тип ресурса: Обзор

DOI:10.17116/jnevro201811809198

Аннотация:
Non-motor disturbances represented by sensory, affective, obsessive-compulsive disorders, cognitive dysfunction, sleep disturbances are often found in patients with dystonia and have a negative impact on their quality of life. The prevalence of sensory and affective disorders and sleep disturbances is above 50[%] in patients with cervical dystonia and is 25[%] in patients with blepharospasm, writing spasm; cognitive dysfunction is found in more than 25[%] of patients with focal dystonia. The relationship of nonmotor, in particular psychiatric disorders, with the impairment of social and everyday life and worsening of quality of life in whole was shown. Common pathophysiological mechanisms of non-motor disorders as well as approaches to treatment of these disorders are discussed. The authors present the results on the positive effect of botulinum toxin therapy that reduces cognitive dysfunction, sensory disorders and depressive syndrome. Non-medication treatment of non-motor disorders in pati
Ключевые слова:
Anxiety; Cognitive impairment; Depression; Dystonia; Sensory disorders; Sleep disturbances; Treatment
botulinum toxin; botulinum toxin; blepharospasm; cervical dystonia; cognitive defect; daily life activity; depression; dystonia; focal dystonia; human; mental disease; mood disorder; muscle spasm; obsessive compulsive disorder; prevalence; quality of life; Review; sensory dysfunction; sleep disorder; blepharospasm; complication; depression; dystonia; dystonic disorder; sleep disorder; Blepharospasm; Botulinum Toxins; Depressive Disorder; Dystonia; Dystonic Disorders; Humans; Quality of Life; Sleep Wake Disorders
Язык текста: Русский
ISSN: 2309-4729
Салоучина Н. И.
Нодель М. Р. Марина Романовна 1971-
Толмачева В. А. Виолетта Александровна 1977-
Salouchina N. I.
Nodel` M. R. Marina Romanovna 1971-
Tolmacheva V. A. Violetta Aleksandrovna 1977-
Non-motor disorders in patients with muscular dystonia
Текст визуальный непосредственный
Журнал неврологии и психиатрии им. C.C. Корсакова
Издательство Медиа Сфера
Т. 118, Вып. 9 С. 98-105
2018
Обзор
Anxiety Cognitive impairment Depression Dystonia Sensory disorders Sleep disturbances Treatment
botulinum toxin botulinum toxin blepharospasm cervical dystonia cognitive defect daily life activity depression dystonia focal dystonia human mental disease mood disorder muscle spasm obsessive compulsive disorder prevalence quality of life Review sensory dysfunction sleep disorder blepharospasm complication depression dystonia dystonic disorder sleep disorder Blepharospasm Botulinum Toxins Depressive Disorder Dystonia Dystonic Disorders Humans Quality of Life Sleep Wake Disorders
Non-motor disturbances represented by sensory, affective, obsessive-compulsive disorders, cognitive dysfunction, sleep disturbances are often found in patients with dystonia and have a negative impact on their quality of life. The prevalence of sensory and affective disorders and sleep disturbances is above 50[%] in patients with cervical dystonia and is 25[%] in patients with blepharospasm, writing spasm; cognitive dysfunction is found in more than 25[%] of patients with focal dystonia. The relationship of nonmotor, in particular psychiatric disorders, with the impairment of social and everyday life and worsening of quality of life in whole was shown. Common pathophysiological mechanisms of non-motor disorders as well as approaches to treatment of these disorders are discussed. The authors present the results on the positive effect of botulinum toxin therapy that reduces cognitive dysfunction, sensory disorders and depressive syndrome. Non-medication treatment of non-motor disorders in pati