Аннотация:
Pectus excavatum (PE) and pectus carinatum (PC) in children are the most common congenital deformities that cause complications in the thoracic organs; however, the role of chondrocytes and cartilage canals in the pathogenesis of these conditions remains unexplored. Objective — to investigate qualitative and quantitative changes of cartilage lacunae and canals in the costal cartilages in children with PE and PC compared to those with normal chests. Subject and methods. Costal cartilages were investigated in 10 children with normal chests (a control group), in 12 children with PE, and in 12 children with PC. Tissue fragments were fixed in 10[%] neutral formalin and embedded in compacted paraffin. Sections were stained with hematoxylin and eosin. Slides were examined by light microscopy. Cartilage lacunae, hyper-and hypolacunar zones, and cartilage canals were morphometrically examined, followed by statistical data analysis. Results. There was a significant decrease in the number of cartil
Ключевые слова:
Cartilage channels; Chondrocytes; Pectus carinatum; Pectus excavatum
child; funnel chest; human; pathology; pigeon thorax; rib cartilage; Child; Costal Cartilage; Funnel Chest; Humans; Pectus Carinatum
Курков А. В. Александр Витальевич 1989-
Пауков В. С. Вячеслав Семенович 1934-
Файзуллин А. Л. Алексей Леонидович 1994-
Шехтер А. Б. Анатолий Борухович 1933-
Kurkov A. V. Aleksandr Vitalyevich 1989-
Paukov V. S. Vyacheslav Semenovich 1934-
Fayzullin A. L. Aleksej Leonidovich 1994-
Shekhter A. B. Anatolij Borukhovich 1933-
Costal cartilage changes in children with pectus excavatum and pectus carinatum
Текст визуальный непосредственный
Архив патологии
Издательство Медиа Сфера
Т. 80, Вып. 5 С. 8-15
2018
Статья
Cartilage channels Chondrocytes Pectus carinatum Pectus excavatum
child funnel chest human pathology pigeon thorax rib cartilage Child Costal Cartilage Funnel Chest Humans Pectus Carinatum
Pectus excavatum (PE) and pectus carinatum (PC) in children are the most common congenital deformities that cause complications in the thoracic organs; however, the role of chondrocytes and cartilage canals in the pathogenesis of these conditions remains unexplored. Objective — to investigate qualitative and quantitative changes of cartilage lacunae and canals in the costal cartilages in children with PE and PC compared to those with normal chests. Subject and methods. Costal cartilages were investigated in 10 children with normal chests (a control group), in 12 children with PE, and in 12 children with PC. Tissue fragments were fixed in 10[%] neutral formalin and embedded in compacted paraffin. Sections were stained with hematoxylin and eosin. Slides were examined by light microscopy. Cartilage lacunae, hyper-and hypolacunar zones, and cartilage canals were morphometrically examined, followed by statistical data analysis. Results. There was a significant decrease in the number of cartil