Bulletin of Experimental Biology and Medicine
Vol.165, Issue6, P. 820-822
Аннотация:
We studied the efficiency of bubbling air as a method of detoxification of the blood plasma and its mixtures with plasma substitutes from CCl4. The efficiency of detoxification depended on the characteristics of the obtained foams: foam forming ability, frequency rate, dispersion, stability of a foam skeleton, syneresis, etc. A hardware-software complex for extracorporeal blood plasma detoxification was developed and the programs for the control and regulation of this process were tested. Physical and mathematical models of toxicant excretion from the body during extracorporal blood detoxification were proposed. Verification of the mathematical model demonstrates high correspondence between the theoretical and experimental data. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Ключевые слова:
blood plasma; extracorporeal detoxification; foaming; foamy air barbotage; toxicant
carbon tetrachloride; foaming agent; plasma substitute; Article; detoxification; dispersion; extracorporeal oxygenation; foam; foaming; mathematical model; physical model; plasma; software; chemistry; computer; dialyzer; diffusion; drug inactivation; gas; human; kinetics; plasma; theoretical model; tissue engineering; Carbon Tetrachloride; Computers; Diffusion; Gases; Humans; Inactivation, Metabolic; Kidneys, Artificial; Kinetics; Models, Theoretical; Plasma; Software; Tissue Engineering
Ershov Y. A.
Khachaturyan M. A. Marina Ashotovna 1945-
Slonskaya T. K. Tat`yana Kimovna 1969-
Ершов Y. А.
Хачатурян М. А. Марина Ашотовна 1945-
Слонская Т. К. Татьяна Кимовна 1969-
Extracorporeal Barbotage Detoxification of the Blood Plasma
Текст визуальный непосредственный
Bulletin of Experimental Biology and Medicine
Springer New York Consultants Bureau
Vol.165, Issue6 P. 820-822
2018
Статья
blood plasma extracorporeal detoxification foaming foamy air barbotage toxicant
carbon tetrachloride foaming agent plasma substitute Article detoxification dispersion extracorporeal oxygenation foam foaming mathematical model physical model plasma software chemistry computer dialyzer diffusion drug inactivation gas human kinetics plasma theoretical model tissue engineering Carbon Tetrachloride Computers Diffusion Gases Humans Inactivation, Metabolic Kidneys, Artificial Kinetics Models, Theoretical Plasma Software Tissue Engineering
We studied the efficiency of bubbling air as a method of detoxification of the blood plasma and its mixtures with plasma substitutes from CCl4. The efficiency of detoxification depended on the characteristics of the obtained foams: foam forming ability, frequency rate, dispersion, stability of a foam skeleton, syneresis, etc. A hardware-software complex for extracorporeal blood plasma detoxification was developed and the programs for the control and regulation of this process were tested. Physical and mathematical models of toxicant excretion from the body during extracorporal blood detoxification were proposed. Verification of the mathematical model demonstrates high correspondence between the theoretical and experimental data. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.