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Medical applications of collagen and collagen-based materials

Shekhter A. B., Fayzullin A. L., Vukolova M. N., Rudenko T. G., Osipycheva V. D., Litvitskij P. F.
Current Medicinal Chemistry
Vol.26, Issue3, P. 506-516
Опубликовано: 2019
Тип ресурса: Статья

DOI:10.2174/0929867325666171205170339

Аннотация:
Collagen and collagen-based materials have been successfully used in medicine for over 50 years. The number of scientific articles about the role of collagen in the construction of scaffolds for tissue engineering has risen precipitously in recent years. The review contains materials about historic and modern applications of collagen in medicine such as soluble collagen injections, solid constructs reconstructed from solution, and decellularized collagen matrices. The analysis of published data proves the efficacy of collagen material in the treatment of chronic wounds, burns, venous and diabetic ulcers, in plastic, reconstructive and general surgery, urology, proctology, gynecology, ophthalmology, otolaryngology, neurosurgery, dentistry, cardiovascular and bone and cartilage surgery, as well as in cosmetology. Further development of collagenoplasty requires addressing the problems of allergic complications, improvement of structure and maximizing therapeutic effects against pathologic
Ключевые слова:
Collagen; Decellularized collagen matrix; Natural polymer; Reconstructed collagen; Scaffold; Tissue engineering
antiinfective agent; collagen; hemostatic agent; biomaterial; collagen; Article; blood vessel; bone regeneration; cartilage; collagen fiber; collagenoplasty; dental practice; heart valve; human; injection; neurosurgery; nonhuman; nutrient; ophthalmology; otorhinolaryngology; plastic surgery; reconstructive surgery; wound healing; chemistry; medicine; Biocompatible Materials; Collagen; Humans; Medicine
Язык текста: Английский
ISSN: 1875-533X
Shekhter A. B. Anatolij Borukhovich 1933-
Fayzullin A. L. Aleksej Leonidovich 1994-
Vukolova M. N. Marina Nikolaevna 1977-
Rudenko T. G. Tat`yana Georgievna 1943-
Osipycheva V. D.
Litvitskij P. F. Petr Frantsevich 1947-
Шехтер А. Б. Анатолий Борухович 1933-
Файзуллин А. Л. Алексей Леонидович 1994-
Вуколова М. Н. Марина Николаевна 1977-
Руденко Т. Г. Татьяна Георгиевна 1943-
Осипyчева В. Д.
Литвицкий П. Ф. Петр Францевич 1947-
Medical applications of collagen and collagen-based materials
Текст визуальный непосредственный
Current Medicinal Chemistry
Bentham Science Publishers
Vol.26, Issue3 P. 506-516
2019
Статья
Collagen Decellularized collagen matrix Natural polymer Reconstructed collagen Scaffold Tissue engineering
antiinfective agent collagen hemostatic agent biomaterial collagen Article blood vessel bone regeneration cartilage collagen fiber collagenoplasty dental practice heart valve human injection neurosurgery nonhuman nutrient ophthalmology otorhinolaryngology plastic surgery reconstructive surgery wound healing chemistry medicine Biocompatible Materials Collagen Humans Medicine
Collagen and collagen-based materials have been successfully used in medicine for over 50 years. The number of scientific articles about the role of collagen in the construction of scaffolds for tissue engineering has risen precipitously in recent years. The review contains materials about historic and modern applications of collagen in medicine such as soluble collagen injections, solid constructs reconstructed from solution, and decellularized collagen matrices. The analysis of published data proves the efficacy of collagen material in the treatment of chronic wounds, burns, venous and diabetic ulcers, in plastic, reconstructive and general surgery, urology, proctology, gynecology, ophthalmology, otolaryngology, neurosurgery, dentistry, cardiovascular and bone and cartilage surgery, as well as in cosmetology. Further development of collagenoplasty requires addressing the problems of allergic complications, improvement of structure and maximizing therapeutic effects against pathologic