Аннотация:
The clinical signs of varicocele typically emerge during the puberty. Varicocele is found in 15[%] of men in the general population and 25-35[%] and 50-80[%] of males presenting with primary and secondary infertility, respectively. Factors contributing to the development and recurrence of varicocele include the abnormalities of the testicular venous drainage and outflow (varicose veins are more common on the left than on the right), the anatomical features of the veins of the testicular and prostatic venous plexus, the patients constitution, predisposition to constipation or diarrhea, physical activity. At present, the genetic defects, including the undifferentiated connective tissue dysplasia (UCTD) with hereditary insufficiency of venous valves and the weakness of the testicular vein walls, are thought to play a key role in the formation of a varicocele. Considering the importance of varicocele in the development of male infertility, the role of the UCTD in varicocele formation warrants a
Ключевые слова:
mechanisms of varicocele development; molecular genetic factors; recurrent varicocele; undifferentiated connective tissue dysplasia
age; complication; connective tissue disease; genetics; human; male; recurrent disease; varicocele; Age Factors; Humans; Male; Recurrence; Undifferentiated Connective Tissue Diseases; Varicocele
Стюденникова В. В.
Севергина Л. О. Любовь Олеговна 1968-
Цариченко Д. Г. Дмитрий Георгиевич 1969-
Исмаилов М. Т. о. Магамед Тахир оглы 1992-
Коровин И. А. Игорь Андреевич 1996-
Рапопорт Л. М. Леонид Моисеевич 1956-
Захаров А. И.
Петрухина Y. В.
Studennikova V. V.
Severgina L. O. Lyubov` Olegovna 1968-
Tsarichenko D. G. Dmitrij Georgievich 1969-
Ismailov M. T. o. Magamed Takhir ogly' 1992-
Korovin I. A. Igor` Andreevich 1996-
Rapoport L. M. Leonid Moiseevich 1956-
Zakharov A. I.
Petrukhina Y. V.
Current view on the pathogenesis of varicocele and the problem of its recurrence
Текст визуальный непосредственный
Урология
Бионика Медиа
Вып. 1 С. 150-154
2018
Статья
mechanisms of varicocele development molecular genetic factors recurrent varicocele undifferentiated connective tissue dysplasia
age complication connective tissue disease genetics human male recurrent disease varicocele Age Factors Humans Male Recurrence Undifferentiated Connective Tissue Diseases Varicocele
The clinical signs of varicocele typically emerge during the puberty. Varicocele is found in 15[%] of men in the general population and 25-35[%] and 50-80[%] of males presenting with primary and secondary infertility, respectively. Factors contributing to the development and recurrence of varicocele include the abnormalities of the testicular venous drainage and outflow (varicose veins are more common on the left than on the right), the anatomical features of the veins of the testicular and prostatic venous plexus, the patients constitution, predisposition to constipation or diarrhea, physical activity. At present, the genetic defects, including the undifferentiated connective tissue dysplasia (UCTD) with hereditary insufficiency of venous valves and the weakness of the testicular vein walls, are thought to play a key role in the formation of a varicocele. Considering the importance of varicocele in the development of male infertility, the role of the UCTD in varicocele formation warrants a