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Covid‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)

Goumenou M., Sarigiannis D., Tsatsakis A., Anesti O., Docea A. O., Petrakis D., Tsoukalas D., Kostoff R., Rakitskii V., Spandidos D. A., Ashner M., Calina D.
Molecular Medicine Reports
Vol.22, Issue1, P. 20-32
Опубликовано: 2020
Тип ресурса: Обзор

DOI:10.3892/mmr.2020.11079

Аннотация:
Italy is currently one of the countries seriously affected by the COVID-19 pandemic. As per 10 April 2020, 147,577 people were found positive in a total of 906,864 tests performed and 18,849 people lost their lives. Among all cases, 70.2[%] of positive, and 79.4[%] of deaths occurred in the provinces of Northern Italy (Lombardi, Emilia Romagna, Veneto and Piemonte), where the outbreak first started. Originally, it was considered that the high number of positive cases and deaths in Italy resulted from COVID-19 initially coming to Italy from China, its presumed country of origin. However, an analysis of the factors that played a role in the extent of this outbreak is needed. Evaluating which factors could be specific for a country and which might contribute the most is nevertheless complex, with accompanying high uncertainty. The purpose of this work is to discuss some of the possible contributing factors and their possible role in the relatively high infection and death rates in Northern It
Ключевые слова:
Coronavirus; COVID-19; Italy; Pandemic diseases; Public health; Risk factors; SARS-CoV-2
age distribution; attitude to illness; clinical evaluation; comorbidity; comparative study; coronavirus disease 2019; diabetes mellitus; environmental factor; epidemic; family; genetic polymorphism; genetic susceptibility; habit; health care; health care organization; health status; human; hypertension; infection rate; Italy; malignant neoplasm; molecular evolution; mortality rate; obesity; physical activity; population density; population health; Review; Severe acute respiratory syndrome coronavirus 2; smoking; social life; virus transmission; article; China; controlled study; Italy; uncertainty
Язык текста: Английский
ISSN: 1791-3004
Goumenou M.
Sarigiannis D.
Tsatsakis A. Aristidis 1957-
Anesti O.
Docea A. O.
Petrakis D.
Tsoukalas D.
Kostoff R.
Rakitskii V.
Spandidos D. A.
Ashner M. Mikhae`l` 1955-
Calina D.
Гоуменоу М.
Саригианнис Д.
Цацакис А. Аристидис 1957-
Анести О.
Доcеа А. О.
Петракис Д.
Цоукалас Д.
Костофф Р.
Ракицкии В.
Спандидос Д. А.
Ашнер М. Михаэль 1955-
Cалина Д.
Covid‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)
Текст визуальный непосредственный
Molecular Medicine Reports
Spandidos Publications Ltd.
Vol.22, Issue1 P. 20-32
2020
Обзор
Coronavirus COVID-19 Italy Pandemic diseases Public health Risk factors SARS-CoV-2
age distribution attitude to illness clinical evaluation comorbidity comparative study coronavirus disease 2019 diabetes mellitus environmental factor epidemic family genetic polymorphism genetic susceptibility habit health care health care organization health status human hypertension infection rate Italy malignant neoplasm molecular evolution mortality rate obesity physical activity population density population health Review Severe acute respiratory syndrome coronavirus 2 smoking social life virus transmission article China controlled study Italy uncertainty
Italy is currently one of the countries seriously affected by the COVID-19 pandemic. As per 10 April 2020, 147,577 people were found positive in a total of 906,864 tests performed and 18,849 people lost their lives. Among all cases, 70.2[%] of positive, and 79.4[%] of deaths occurred in the provinces of Northern Italy (Lombardi, Emilia Romagna, Veneto and Piemonte), where the outbreak first started. Originally, it was considered that the high number of positive cases and deaths in Italy resulted from COVID-19 initially coming to Italy from China, its presumed country of origin. However, an analysis of the factors that played a role in the extent of this outbreak is needed. Evaluating which factors could be specific for a country and which might contribute the most is nevertheless complex, with accompanying high uncertainty. The purpose of this work is to discuss some of the possible contributing factors and their possible role in the relatively high infection and death rates in Northern It