Hypervitaminosis B12 - A new marker and predictor of prognostically unfavorable diseases
Подзолков В. И., Драгомирецкая Н. А., Дамбаева О. Т., Аувинен С. Т., Медведев И. Д.
Терапевтический архив
Т. 91, Вып. 8, С. 160-167
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.26442/00403660.2019.08.000378
Аннотация:
A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases. © 2019 Consilium Medikum. All rights reserved.
Ключевые слова:
Hemoblastosis; Hypercobalaminemia; Hypervitaminosis B12; Liver diseases
biological marker; cyanocobalamin; B12 deficiency; blood; human; kidney disease; liver; liver disease; Biomarkers; Humans; Kidney Diseases; Liver; Liver Diseases; Vitamin B 12; Vitamin B 12 Deficiency
Язык текста: Русский
ISSN: 2309-5342
Подзолков В. И. Валерий Иванович 1948-
Драгомирецкая Н. А. Наталья Александровна 1978-
Дамбаева О. Т.
Аувинен С. Т.
Медведев И. Д. Иван Дмитриевич 1982-
Podzolkov V. I. Valerij Ivanovich 1948-
Dragomiretskaya N. A. Natal`ya Aleksandrovna 1978-
Dambaeva O. T.
Auvinen S. T.
Medvedev I. D. Ivan Dmitrievich 1982-
Hypervitaminosis B12 - A new marker and predictor of prognostically unfavorable diseases
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 91, Вып. 8 С. 160-167
2019
Статья
Hemoblastosis Hypercobalaminemia Hypervitaminosis B12 Liver diseases
biological marker cyanocobalamin B12 deficiency blood human kidney disease liver liver disease Biomarkers Humans Kidney Diseases Liver Liver Diseases Vitamin B 12 Vitamin B 12 Deficiency
A high serum vitamin B12 level (hypercobalaminemia) is a underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, which are related to defects in tissue uptake of vitamin B12. The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases. © 2019 Consilium Medikum. All rights reserved.