Аннотация:
Invasive coronary angiography (CAG) with simultaneous measurement of fractional blood flow reserve (FFR) is a reference method for assessing the functional significance of coronary artery stenotic lesions in patients with coronary heart disease (CHD). Computed tomographic angiography (CTA) as an alternative non-invasive method of visualization of the coronary bed has high diagnostic accuracy and is included in the algorithm for examining patients with low and medium-risk coronary artery disease. Purpose. To describe the mathematical principles and results of clinical validation of FFRCTA to assess myocardial ischemia. Material and methods. Data analysis of domestic and foreign literature, scientific publications, electronic resources. Results. With the help of mathematical modeling of the coronary blood flow using the laws of hydrodynamics, it became possible to calculate the FFR using data from the CTA (FFR CTA). The results of the large multicenter research DISCOVER-FLOW, DeFACTO and
Ключевые слова:
Computed tomographic angiography (CTA); Coronary arteries; Fractional blood flow reserve (FFR); Mathematical modeling
Article; computed tomographic angiography; coronary angiography; coronary artery; coronary artery blood flow; coronary artery disease; diagnostic accuracy; fractional flow reserve; heart muscle ischemia; human; hydrodynamics; mathematical model
Терновой С. К. Сергей Константинович 1948-
Чеповскиy А. М.
Веселова Т. Н.
Борисенко В. В.
Серова Н. С. Наталья Сергеевна 1979-
Ternovoj S. K. Sergej Konstantinovich 1948-
Chepovskiy A. M.
Veselova T. N.
Borisenko V. V.
Serova N. S. Natal`ya Sergeevna 1979-
Mathematical modeling of coronary blood flow to assess the functional significance of stenotic lesion by computed tomography [МАТЕМАТИЧЕСКОЕ МОДЕЛИРОВАНИЕ КОРОНАРНОГО КРОВОТОКА ДЛЯ ОЦЕНКИ ФУНКЦИОНАЛЬНОЙ ЗНАЧИМОСТИ СТЕНОТИЧЕСКОГО ПОРАЖЕНИЯ ПО ДАННЫМ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ]
Mathematical modeling of coronary blood flow to assess the functional significance of stenotic lesion by computed tomography [МАТЕМАТИЧЕСКОЕ...
Текст визуальный непосредственный
Российский электронный журнал лучевой диагностики
Национальный конгресс лучевых диагностов
Т. 9, Вып. 2 С. 205-212
2019
Статья
Computed tomographic angiography (CTA) Coronary arteries Fractional blood flow reserve (FFR) Mathematical modeling
Article computed tomographic angiography coronary angiography coronary artery coronary artery blood flow coronary artery disease diagnostic accuracy fractional flow reserve heart muscle ischemia human hydrodynamics mathematical model
Invasive coronary angiography (CAG) with simultaneous measurement of fractional blood flow reserve (FFR) is a reference method for assessing the functional significance of coronary artery stenotic lesions in patients with coronary heart disease (CHD). Computed tomographic angiography (CTA) as an alternative non-invasive method of visualization of the coronary bed has high diagnostic accuracy and is included in the algorithm for examining patients with low and medium-risk coronary artery disease. Purpose. To describe the mathematical principles and results of clinical validation of FFRCTA to assess myocardial ischemia. Material and methods. Data analysis of domestic and foreign literature, scientific publications, electronic resources. Results. With the help of mathematical modeling of the coronary blood flow using the laws of hydrodynamics, it became possible to calculate the FFR using data from the CTA (FFR CTA). The results of the large multicenter research DISCOVER-FLOW, DeFACTO and