Аннотация:
Aim. To determine the frequency, clinical and morphological features of a nephropathy with C1q deposits in chronic glomerulonephritis adult patients. Materials and methods. 296 specimens of kidneys of patients with a chronic glomerulonephritis (CGN) from 2014 for 2018 were analyzed. At the first step, specimens with C1q deposits in glomeruli revealed by immunofluorescent method were chosen. Lupus nephritis and primary membranoproliferative glomerulonephritis were exclusion criteria. At the second step, the retrospective analysis of the clinical characteristics was carried out. Results and discussion. Deposits of C1q in kidneys at 12 of 296 (4.05[%]) CGN were revealed, m:f ratio 2:1. Average age of the beginning of a disease was 32.1±14.7 years. At a morphological research in 8 membranous nephropathy (MN), in 2 mesangioproliferative glomerulonephritis (MesPGN), in 2 - nephrosclerosis was revealed. Among 12 patients in 5 the disease debuted a nephrotic syndrome, at the others - a proteinur
Чеботарева Н. В. Наталья Викторовна 1976-
Виноградов А. А.
Гришина А. Н. Алена Николаевна 1987-
Лысенко Л. В. Лидия Владимировна 1937-
Варшавский В. А. Владимир Анатольевич 1941-
Chebotareva N. V. Natal`ya Viktorovna 1976-
Vinogradov A. A.
Grishina A. N. Alena Nikolaevna 1987-
Ly'senko L. V. Lidiya Vladimirovna 1937-
Varshavskij V. A. Vladimir Anatolyevich 1941-
Clinical and pathologic features of nephropathy with C1q deposits
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 91, Вып. 6 С. 57-61
2019
Статья
C1q-nephropathy Chronic glomerulonephritis Kidney biopsy
Aim. To determine the frequency, clinical and morphological features of a nephropathy with C1q deposits in chronic glomerulonephritis adult patients. Materials and methods. 296 specimens of kidneys of patients with a chronic glomerulonephritis (CGN) from 2014 for 2018 were analyzed. At the first step, specimens with C1q deposits in glomeruli revealed by immunofluorescent method were chosen. Lupus nephritis and primary membranoproliferative glomerulonephritis were exclusion criteria. At the second step, the retrospective analysis of the clinical characteristics was carried out. Results and discussion. Deposits of C1q in kidneys at 12 of 296 (4.05[%]) CGN were revealed, m:f ratio 2:1. Average age of the beginning of a disease was 32.1±14.7 years. At a morphological research in 8 membranous nephropathy (MN), in 2 mesangioproliferative glomerulonephritis (MesPGN), in 2 - nephrosclerosis was revealed. Among 12 patients in 5 the disease debuted a nephrotic syndrome, at the others - a proteinur