Аннотация:
The ability of drugs to have an ototoxic effect has been studied for a long time, however, the true prevalence of this undesirable phenomenon is unknown, which is due to the use of various audiological protocols, a wide range of reactions to drugs in different ethnic groups, and most importantly, the lack of caution with regard to otological symptoms due to their reversibility or lack of immediate threat to life. Drug-induced ototoxicity is a functional disorder of the inner ear (cochlea and/or vestibular apparatus) or eighth pair of cranial nerves. Pharmacotherapy, associated with the development of ototoxic drug reactions, may remain undervalued for a long time, often until irreversible hearing impairment is formed. The most frequently prescribed drugs that cause ototoxic phenomena include anticancer drugs, antibacterial drugs of the aminoglycoside group, loop diuretics, calcium channel blockers, non-steroidal anti-inflammatory drugs, antimalarial drugs, salicylates, etc. Monitoring
Ключевые слова:
Drug-induced hearing loss; Drug-induced ototoxicity; Hearing loss; Ototoxicity; Undesirable drug reactions
aminoglycoside; antiinfective agent; adverse drug reaction; drug effect; hearing impairment; human; inner ear; Aminoglycosides; Anti-Bacterial Agents; Deafness; Drug-Related Side Effects and Adverse Reactions; Ear, Inner; Hearing Loss; Humans
Остроумова О. Д. Ольга Дмитриевна 1968-
Ших Е. В. Евгения Валерьевна 1962-
Реброва Е. В. Екатерина Владиславовна 1987-
Рязанова А. Y.
Переверзев А. П.
Ostroumova O. D. Ol`ga Dmitrievna 1968-
Shikh E. V. Evgeniya Valeryevna 1962-
Rebrova E. V. Ekaterina Vladislavovna 1987-
Ryazanova A. Y.
Pereverzev A. P.
Drug-induced hearing loss as a manifestation of drug-induced ototoxicity
Текст визуальный непосредственный
Вестник оториноларингологии
Издательство Медиа Сфера
Т. 84, Вып. 4 С. 72-80
2019
Статья
Drug-induced hearing loss Drug-induced ototoxicity Hearing loss Ototoxicity Undesirable drug reactions
aminoglycoside antiinfective agent adverse drug reaction drug effect hearing impairment human inner ear Aminoglycosides Anti-Bacterial Agents Deafness Drug-Related Side Effects and Adverse Reactions Ear, Inner Hearing Loss Humans
The ability of drugs to have an ototoxic effect has been studied for a long time, however, the true prevalence of this undesirable phenomenon is unknown, which is due to the use of various audiological protocols, a wide range of reactions to drugs in different ethnic groups, and most importantly, the lack of caution with regard to otological symptoms due to their reversibility or lack of immediate threat to life. Drug-induced ototoxicity is a functional disorder of the inner ear (cochlea and/or vestibular apparatus) or eighth pair of cranial nerves. Pharmacotherapy, associated with the development of ototoxic drug reactions, may remain undervalued for a long time, often until irreversible hearing impairment is formed. The most frequently prescribed drugs that cause ototoxic phenomena include anticancer drugs, antibacterial drugs of the aminoglycoside group, loop diuretics, calcium channel blockers, non-steroidal anti-inflammatory drugs, antimalarial drugs, salicylates, etc. Monitoring