The role of adjuvant radiotherapy after surgery for upper and lower urinary tract urothelial carcinoma: A systematic review
Iwata T., Kimura S., Abufaraj M., Janisch F., Karakiewicz P. I., Seebacher V., Rouprêt M., Nasu Y., Shariat Sh.
Urologic Oncology
Vol.37, Issue10, P. 659-671
Опубликовано: 2019
Тип ресурса: Обзор
DOI:10.1016/j.urolonc.2019.05.021
Аннотация:
Objectives: The role of adjuvant radiotherapy (ART) in patients with bladder cancer (BCa) and upper tract urothelial carcinoma (UTUC) is controversial. We systematically evaluated the oncologic efficacy of ART and its associated toxicity in patients treated with surgery and ART for BCa and UTUC. Materials and method: We performed a literature search on December 2018 using MEDLINE, Web of Science, Cochrane databases and Scopus according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. Fourteen BCa studies and 14 UTUC studies were included in this systematic review. The data were too scarce and heterogeneous for meta-analytical analysis. Results: The quality and quantity of the data on ART in BCa and UTUC patients are limited. The combination of ART and chemotherapy appears to be beneficial in patients with locally advanced BCa or UTUC. The early and late adverse effects of ART are decreasing reflecting the progress in radiation technology. Conclusions:
Ключевые слова:
Adjuvant radiotherapy; Bladder cancer; Recurrence; Upper tract urothelial carcinoma
adjuvant radiotherapy; human; pathology; procedures; survival analysis; transitional cell carcinoma; urinary tract tumor; Carcinoma, Transitional Cell; Humans; Radiotherapy, Adjuvant; Survival Analysis; Urologic Neoplasms
Язык текста: Английский
ISSN: 1873-2496
Iwata T.
Kimura S.
Abufaraj M.
Janisch F.
Karakiewicz P. I.
Seebacher V.
Rouprêt M.
Nasu Y.
Shariat Sh. Sharokh 1973-
Иwата Т.
Кимура С.
Абуфарай М.
Йанисч Ф.
Каракиеwиcз П. И.
Сеебачер В.
Роупрêт М.
Насу Y.
Шариат Ш. Шарох 1973-
The role of adjuvant radiotherapy after surgery for upper and lower urinary tract urothelial carcinoma: A systematic review
Текст визуальный непосредственный
Urologic Oncology
Elsevier Science Publisher B.V.
Vol.37, Issue10 P. 659-671
2019
Обзор
Adjuvant radiotherapy Bladder cancer Recurrence Upper tract urothelial carcinoma
adjuvant radiotherapy human pathology procedures survival analysis transitional cell carcinoma urinary tract tumor Carcinoma, Transitional Cell Humans Radiotherapy, Adjuvant Survival Analysis Urologic Neoplasms
Objectives: The role of adjuvant radiotherapy (ART) in patients with bladder cancer (BCa) and upper tract urothelial carcinoma (UTUC) is controversial. We systematically evaluated the oncologic efficacy of ART and its associated toxicity in patients treated with surgery and ART for BCa and UTUC. Materials and method: We performed a literature search on December 2018 using MEDLINE, Web of Science, Cochrane databases and Scopus according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. Fourteen BCa studies and 14 UTUC studies were included in this systematic review. The data were too scarce and heterogeneous for meta-analytical analysis. Results: The quality and quantity of the data on ART in BCa and UTUC patients are limited. The combination of ART and chemotherapy appears to be beneficial in patients with locally advanced BCa or UTUC. The early and late adverse effects of ART are decreasing reflecting the progress in radiation technology. Conclusions: