An enigmatic catalase of Blastocrithidia
Bianchi C., Kostygov A. Y., Kraeva N., Záhonová K., Horáková E., Sobotka R., Lukeš J., Yurchenko V.
Molecular and Biochemical Parasitology
Vol.232, Num.111199
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1016/j.molbiopara.2019.111199
Аннотация:
Here we report that trypanosomatid flagellates of the genus Blastocrithidia possess catalase. This enzyme is not phylogenetically related to the previously characterized catalases in other monoxenous trypanosomatids, suggesting that their genes have been acquired independently. Surprisingly, Blastocrithidia catalase is less enzymatically active, compared to its counterpart from Leptomonas pyrrhocoris, posing an intriguing biological question why this gene has been retained in the evolution of trypanosomatids. © 2019
Ключевые слова:
Catalase; Oxygen peroxide; Trypanosomatidae
catalase; catalase; hydrogen peroxide; protozoal protein; Article; Blastocrithidia; controlled study; enzyme activity; genetic analysis; Leptomonas; nonhuman; phylogeny; priority journal; Trypanosomatidae; amino acid sequence; chemistry; classification; enzymology; genetics; metabolism; molecular evolution; sequence alignment; Trypanosomatidae; Amino Acid Sequence; Catalase; Evolution, Molecular; Hydrogen Peroxide; Phylogeny; Protozoan Proteins; Sequence Alignment; Trypanosomatina
Язык текста: Английский
ISSN: 1872-9428
Bianchi C.
Kostygov A. Y.
Kraeva N.
Záhonová K.
Horáková E.
Sobotka R.
Lukeš J.
Yurchenko V. Vyacheslav 1972-
Бианчи C.
Костyгов А. Y.
Краева Н.
Зáхоновá К.
Хорáковá Е.
Соботка Р.
Лукеš Й.
Юрченко В. Вячеслав 1972-
An enigmatic catalase of Blastocrithidia
Текст визуальный непосредственный
Molecular and Biochemical Parasitology
Elsevier Science Publisher B.V.
Vol.232 Num.111199
2019
Статья
Catalase Oxygen peroxide Trypanosomatidae
catalase catalase hydrogen peroxide protozoal protein Article Blastocrithidia controlled study enzyme activity genetic analysis Leptomonas nonhuman phylogeny priority journal Trypanosomatidae amino acid sequence chemistry classification enzymology genetics metabolism molecular evolution sequence alignment Trypanosomatidae Amino Acid Sequence Catalase Evolution, Molecular Hydrogen Peroxide Phylogeny Protozoan Proteins Sequence Alignment Trypanosomatina
Here we report that trypanosomatid flagellates of the genus Blastocrithidia possess catalase. This enzyme is not phylogenetically related to the previously characterized catalases in other monoxenous trypanosomatids, suggesting that their genes have been acquired independently. Surprisingly, Blastocrithidia catalase is less enzymatically active, compared to its counterpart from Leptomonas pyrrhocoris, posing an intriguing biological question why this gene has been retained in the evolution of trypanosomatids. © 2019