New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections
Rafeie M., Hosseinzadeh S., Huang J., Mihandoust A., Ibragimi V. M. M., Taylor R. A.
Biomicrofluidics
Vol.13, Issue3, Num.034118
Опубликовано: 2019
Тип ресурса: Статья
Аннотация:
Curved microchannels allow controllable microparticle focusing, but a full understanding of particle behavior has been limited - even for simple rectangular and trapezoidal shapes. At present, most microfluidic particle separation literature is dedicated to adding "internal" complexity (via sheath flow or obstructions) to relatively simple cross-sectional channel shapes. We propose that, with sufficient understanding of particle behavior, an equally viable pathway for microparticle focusing could utilize complex "external" cross-sectional shapes. By investigating three novel, complex spiral microchannels, we have found that it is possible to passively focus (6, 10, and 13 μm) microparticles in the middle of a convex channel. Also, we found that in concave and jagged channel designs, it is possible to create multiple, tight focusing bands. In addition to these performance benefits, we report an "additive rule" herein, which states that complex channels can be considered as multiple, ind
Ключевые слова:
Additives; Focusing; Microchannels; Complex cross-sections; Cross-sectional shape; Curved microchannel; Experimental and numerical analysis; Inertial microfluidics; Particle separation; Performance benefits; Suspended particles; Microfluidics
Язык текста: Английский
ISSN: 1932-1058
Rafeie M.
Hosseinzadeh S.
Huang J.
Mihandoust A.
Ibragimi V. M. M. Varkiani Madzhid Modzhtaba 1983-
Taylor R. A.
Рафеие М.
Хоссеинзадех С.
Хуанг Й.
Михандоуст А.
Ибрагими В. М. М. Варкиани Маджид Моджтаба 1983-
Тайлор Р. А.
New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections
Текст визуальный непосредственный
Biomicrofluidics
American Institute of Physics
Vol.13, Issue3 Num.034118
2019
Статья
Additives Focusing Microchannels Complex cross-sections Cross-sectional shape Curved microchannel Experimental and numerical analysis Inertial microfluidics Particle separation Performance benefits Suspended particles Microfluidics
Curved microchannels allow controllable microparticle focusing, but a full understanding of particle behavior has been limited - even for simple rectangular and trapezoidal shapes. At present, most microfluidic particle separation literature is dedicated to adding "internal" complexity (via sheath flow or obstructions) to relatively simple cross-sectional channel shapes. We propose that, with sufficient understanding of particle behavior, an equally viable pathway for microparticle focusing could utilize complex "external" cross-sectional shapes. By investigating three novel, complex spiral microchannels, we have found that it is possible to passively focus (6, 10, and 13 μm) microparticles in the middle of a convex channel. Also, we found that in concave and jagged channel designs, it is possible to create multiple, tight focusing bands. In addition to these performance benefits, we report an "additive rule" herein, which states that complex channels can be considered as multiple, ind