Brain imaging of the cortex in ADHD: A coordinated analysis of large-scale clinical and population-based samples
Hoogman M., Muetzel R., Guimaraes J. P., Shumskaya E., Mennes M., Zwiers M. P., Jahanshad N., Sudre G., Wolfers T., Earl E. A., Soliva V. J. C., Vives-Gilabert Y., Khadka S., Novotny S. E., Hartman C. A., Heslenfeld D. J., Schweren L. J. S., Ambrosino S., Oranje B., De Z. O. P., Chaim-Avancini T. M., Rosa P. G. P., Zanetti M. V., Malpas C. B., Kohls G., Von P. G. G., Seitz J., Biederman J., Doyle A. E., Dale A. M., van E. T. G. M., Epstein J. N., Jernigan T. L., Baur-Streubel R., Ziegler G. C., Zierhut K. C., Schrantee A., Høvik M. F., Lundervold A. J., Kelly C., McCarthy H., Skokauskas N., O'Gorman T. R. L., Calvo A., Lera-Miguel S., Nicolau R., Chantiluke K. C., Christakou A., Vance A., Cercignani M., Gabel M. C., Asherson P., Baumeister S., Brandeis D., Hohmann S., Bramati I. E., Tovar-Moll F., Fallgatter A. J., Kardatzki B., Schwarz L., Anikin A., Baranov A. A., Gogberashvili T., Kapilushniy D., Solovieva A., El M. H., White T., Karkashadze G., Namazova-Baranova L. S., Ethofer T., Mattos P., Banaschewski T., Coghill D.
American Journal of Psychiatry
Vol.176, Issue7, P. 531-542
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1176/appi.ajp.2019.18091033
Аннотация:
Objective: Neuroimaging studies show structural alterations of various brain regions in children and adults with attention deficit hyperactivity disorder (ADHD), although nonrepli-cations are frequent. The authors sought to identify cortical characteristics related to ADHD using large-scale studies. Methods: Cortical thickness and surface area (based on the Desikan–Killiany atlas) were compared between case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers. To assess familial effects on cortical measures, case subjects, unaffected siblings, and control subjects in the NeuroIMAGE study (N=506) were compared. Associations of the attention scale from the Child Behavior Checklist with cortical measures were determined in a pediatric population sample (Generation-R, N=2,707). Results: In the ENIGMA-ADHD sample, lower surface area values were found in children with ADHD, mainly in frontal, c
Ключевые слова:
adolescent; adult; Article; attention deficit disorder; brain cortex; brain region; case control study; child; Child Behavior Checklist; cingulate gyrus; clinical feature; cohort analysis; comorbidity; comparative study; controlled study; cortical thickness (brain); disease severity; female; human; image analysis; intelligence quotient; major clinical study; male; neuroimaging; neurologic disease assessment; nuclear magnetic resonance imaging; priority journal; sex; surface area; symptom; age; attention deficit disorder; brain cortex; diagnostic imaging; middle aged; neuroimaging; pathology; pathophysiology; preschool child; psychological rating scale; sex factor; young adult; Adolescent; Adult; Age Factors; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Psychiatric Status Rating Scales; Sex Factors; Young Adult
Язык текста: Английский
ISSN: 1535-7228
Hoogman M.
Muetzel R.
Guimaraes J. P.
Shumskaya E.
Mennes M.
Zwiers M. P.
Jahanshad N.
Sudre G.
Wolfers T.
Earl E. A.
Soliva V. J. C. Vila J.C.
Vives-Gilabert Y.
Khadka S.
Novotny S. E.
Hartman C. A.
Heslenfeld D. J.
Schweren L. J. S.
Ambrosino S.
Oranje B.
De Z. O. P. Zeeuw Oranje P.
Chaim-Avancini T. M.
Rosa P. G. P.
Zanetti M. V.
Malpas C. B.
Kohls G.
Von P. G. G. Polier G.G.
Seitz J.
Biederman J.
Doyle A. E.
Dale A. M.
van E. T. G. M. Erp T.G.M.
Epstein J. N.
Jernigan T. L.
Baur-Streubel R.
Ziegler G. C.
Zierhut K. C.
Schrantee A.
Høvik M. F.
Lundervold A. J.
Kelly C.
McCarthy H.
Skokauskas N.
O'Gorman T. R. L. Tuura R.L.
Calvo A.
Lera-Miguel S.
Nicolau R.
Chantiluke K. C.
Christakou A.
Vance A.
Cercignani M.
Gabel M. C.
Asherson P.
Baumeister S.
Brandeis D.
Hohmann S.
Bramati I. E.
Tovar-Moll F.
Fallgatter A. J.
Kardatzki B.
Schwarz L.
Anikin A.
Baranov A. A. Aleksandr Aleksandrovich 1941-
Gogberashvili T.
Kapilushniy D.
Solovieva A.
El M. H. Marroun H.
White T.
Karkashadze G.
Namazova-Baranova L. S. Lejla Sejmurovna 1963-
Ethofer T.
Mattos P.
Banaschewski T.
Coghill D.
Хоогман М.
Муетзел Р.
Гуимараес Й. П.
Шумскайа Е.
Меннес М.
Зwиерс М. П.
Йаханшад Н.
Судре Г.
Wолферс Т.
Еарл Е. А.
Солива В. Й. C. Вила Й.C.
Вивес-Гилаберт Y.
Хадка С.
Новотнy С. Е.
Хартман C. А.
Хесленфелд Д. Й.
Счwерен Л. Й. С.
Амбросино С.
Оранйе Б.
Де З. О. П. Зееуw Оранйе П.
Чаим-Аванcини Т. М.
Роса П. Г. П.
Занетти М. В.
Малпас C. Б.
Кохлс Г.
Вон П. Г. Г. Полиер Г.Г.
Сеитз Й.
Биедерман Й.
Доyле А. Е.
Дале А. М.
ван Е. Т. Г. М. Ерп Т.Г.М.
Епстеин Й. Н.
Йерниган Т. Л.
Баур-Стреубел Р.
Зиеглер Г. C.
Зиерхут К. C.
Счрантее А.
Хøвик М. Ф.
Лундерволд А. Й.
Келлy C.
МcCартхy Х.
Скокаускас Н.
О'Горман Т. Р. Л. Тюура Р.Л.
Cалво А.
Лера-Мигуел С.
Ниcолау Р.
Чантилуке К. C.
Чристакоу А.
Ванcе А.
Cерcигнани М.
Габел М. C.
Ашерсон П.
Баумеистер С.
Брандеис Д.
Хохманн С.
Брамати И. Е.
Товар-Молл Ф.
Фаллгаттер А. Й.
Кардатзки Б.
Счwарз Л.
Аникин А.
Баранов А. А. Александр Александрович 1941-
Гогберашвили Т.
Капилушниy Д.
Соловиева А.
Ел М. Х. Марроун Х.
Wхите Т.
Каркашадзе Г.
Намазова-Баранова Л. С. Лейла Сеймуровна 1963-
Етхофер Т.
Маттос П.
Банасчеwски Т.
Cогхилл Д.
Brain imaging of the cortex in ADHD: A coordinated analysis of large-scale clinical and population-based samples
Текст визуальный непосредственный
American Journal of Psychiatry
Proquest Academic Research Library
Vol.176, Issue7 P. 531-542
2019
Статья
adolescent adult Article attention deficit disorder brain cortex brain region case control study child Child Behavior Checklist cingulate gyrus clinical feature cohort analysis comorbidity comparative study controlled study cortical thickness (brain) disease severity female human image analysis intelligence quotient major clinical study male neuroimaging neurologic disease assessment nuclear magnetic resonance imaging priority journal sex surface area symptom age attention deficit disorder brain cortex diagnostic imaging middle aged neuroimaging pathology pathophysiology preschool child psychological rating scale sex factor young adult Adolescent Adult Age Factors Attention Deficit Disorder with Hyperactivity Case-Control Studies Cerebral Cortex Child Child, Preschool Female Humans Magnetic Resonance Imaging Male Middle Aged Neuroimaging Psychiatric Status Rating Scales Sex Factors Young Adult
Objective: Neuroimaging studies show structural alterations of various brain regions in children and adults with attention deficit hyperactivity disorder (ADHD), although nonrepli-cations are frequent. The authors sought to identify cortical characteristics related to ADHD using large-scale studies. Methods: Cortical thickness and surface area (based on the Desikan–Killiany atlas) were compared between case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers. To assess familial effects on cortical measures, case subjects, unaffected siblings, and control subjects in the NeuroIMAGE study (N=506) were compared. Associations of the attention scale from the Child Behavior Checklist with cortical measures were determined in a pediatric population sample (Generation-R, N=2,707). Results: In the ENIGMA-ADHD sample, lower surface area values were found in children with ADHD, mainly in frontal, c