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Treatment of habitual pregnancy miscarriage of various origins

Unanyan A.L., Pivazyan L.G., Zakaryan A.A., Siordiya A.A., Ishchenko A.I.
Архив акушерства и гинекологии им. В.Ф. Снегирева
Т. 9, № 1, С. 13-21
Опубликовано: 15 ЯНВ02 2022
Тип ресурса: Статья; Обзор

DOI:10.17816/2313-8726-2022-9-1-13-21

Аннотация:

Habitual pregnancy miscarriage is one of the serious problems of reproductive health in the modern world. Habitual miscarriage is defined as the spontaneous termination of two or more pregnancies before the fetus reaches viability from conception to 24 weeks of pregnancy. However, some differences of opinion are determined among specialists in habitual miscarriage. Some experts in their clinical practice for habitual miscarriages use the definition of three or more consecutive miscarriages. Habitual miscarriage occurrence varies from 0.5 to 2.3[%], but the exact prevalence is very difficult to estimate, which depends on the used definition. The pathogenesis of habitual miscarriage is determined based on the age of the mother and the gestational age of the fetus. Habitual miscarriage can be caused by chromosomal errors, autoimmune disorders, endometrial dysfunction, endocrinopathies, hormonal and metabolic disorders, infections, and uterine anatomical defects. Currently available treatments target suspected risk factors for miscarriage, although the effectiveness of many medical interventions appears to be controversial.

This study aimed to evaluate the effectiveness of treatments for habitual miscarriage of various origins, such as antiphospholipid syndrome, subclinical hypothyroidism, and idiopathic habitual miscarriage.

Язык текста: Русский
ISSN: 2313-8726
Unanyan A.L. Ara L.
Pivazyan L.G. Laura G.
Zakaryan A.A. Araksya A.
Siordiya A.A. Archil A.
Ishchenko A.I. Anatoliy I.
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
Treatment of habitual pregnancy miscarriage of various origins
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 9, № 1 С. 13-21
2022
привычное невынашивание беременности
habitual miscarriage
самопроизвольный аборт
spontaneous abortion
антифосфолипидный синдром
antiphospholipid syndrome
субклинический гипотиреоз
subclinical hypothyroidism
идиопатическое привычное невынашивание беременности
idiopathic habitual miscarriage
Статья
Обзор

Habitual pregnancy miscarriage is one of the serious problems of reproductive health in the modern world. Habitual miscarriage is defined as the spontaneous termination of two or more pregnancies before the fetus reaches viability from conception to 24 weeks of pregnancy. However, some differences of opinion are determined among specialists in habitual miscarriage. Some experts in their clinical practice for habitual miscarriages use the definition of three or more consecutive miscarriages. Habitual miscarriage occurrence varies from 0.5 to 2.3[%], but the exact prevalence is very difficult to estimate, which depends on the used definition. The pathogenesis of habitual miscarriage is determined based on the age of the mother and the gestational age of the fetus. Habitual miscarriage can be caused by chromosomal errors, autoimmune disorders, endometrial dysfunction, endocrinopathies, hormonal and metabolic disorders, infections, and uterine anatomical defects. Currently available treatments target suspected risk factors for miscarriage, although the effectiveness of many medical interventions appears to be controversial.

This study aimed to evaluate the effectiveness of treatments for habitual miscarriage of various origins, such as antiphospholipid syndrome, subclinical hypothyroidism, and idiopathic habitual miscarriage.