Аннотация:
The discovery of germline stem cells in adult human ovaries is one of the most remarkable yet controversial findings in modern developmental biology. In the present article, a brief overview is given on ovarian stem cells types, origin, morphofunctional features and similarities to testicular stem cells. The physiological role of postnatal neo-oogenesis and its possible participation in the pathogenesis of some gynecological diseases are discussed. Particular attention is paid to the prospects for practical application to the discovery in reproductive medicine.
Shestakova M.A. Mayya A.
Proskurnina E.V. Elena V.
Fedorova M.V. Mariya V.
Sosnova E.A. Elena A.
«Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России
N.I. Pirogov Russian National Research Medical University
N.P. Bochkov Research Centre for Medical Genetics
«Московский государственный университет им. М.В. Ломоносова»
M.V. Lomonosov Moscow State University
Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Ovarian stem cells: a mini-review
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 7, № 2 С. 60-66
2020
ооциты
oocytes
гаметы
germ cells
стволовые клетки
stem cells
оогенез
oogenesis
Статья
The discovery of germline stem cells in adult human ovaries is one of the most remarkable yet controversial findings in modern developmental biology. In the present article, a brief overview is given on ovarian stem cells types, origin, morphofunctional features and similarities to testicular stem cells. The physiological role of postnatal neo-oogenesis and its possible participation in the pathogenesis of some gynecological diseases are discussed. Particular attention is paid to the prospects for practical application to the discovery in reproductive medicine.