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Pathophysiological role of free radical processes in pregnancies end in miscarriage

Sosnova E.A., Bolevich S.B., Pokaleneva M.S.
Архив акушерства и гинекологии им. В.Ф. Снегирева
Т. 3, № 3, С. 136-140
Опубликовано: 15 2016
Тип ресурса: Статья

DOI:10.18821/2313-8726-2016-3-3-136-140

Аннотация:
Pregnancy end in miscarriage proves to be the one of the main problems of modern obstetrics and gynecology. Miscarriage rate currently accounts for 15-27[%]. Among the causes of miscarriage there are discriminated genetic, anatomic, endocrine, infectious, immunologic, and thrombophilic factors. In the exclusion of all of above mentioned reasons the genesis of spontaneous abortion is considered to be unclear (idiopathic). In recent years, more and more often the attention of clinicians is attracted by pathophysiological aspects of the participation offree radical processes in molecular and cellular mechanisms of the development of alteration in pregnancy end in miscarriage. So far, information both on the generation of reactive oxygen species (ROS) by leukocytes and the state ofprotective antioxidant system in women with habitual loss ofpregnancy has failed to be systematized.
Язык текста: Русский
ISSN: 2313-8726
Sosnova E.A. Elena A.
Bolevich S.B.
Pokaleneva M.S. M. Sh
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
Pathophysiological role of free radical processes in pregnancies end in miscarriage
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 3, № 3 С. 136-140
2016
свободнорадикальные процессы
free-radical processes
невынашивание беременности
miscarriage
Статья
Pregnancy end in miscarriage proves to be the one of the main problems of modern obstetrics and gynecology. Miscarriage rate currently accounts for 15-27[%]. Among the causes of miscarriage there are discriminated genetic, anatomic, endocrine, infectious, immunologic, and thrombophilic factors. In the exclusion of all of above mentioned reasons the genesis of spontaneous abortion is considered to be unclear (idiopathic). In recent years, more and more often the attention of clinicians is attracted by pathophysiological aspects of the participation offree radical processes in molecular and cellular mechanisms of the development of alteration in pregnancy end in miscarriage. So far, information both on the generation of reactive oxygen species (ROS) by leukocytes and the state ofprotective antioxidant system in women with habitual loss ofpregnancy has failed to be systematized.