Аннотация:
The review presents current information on the predictive diagnosis of preeclampsia. The data of instrumental and laboratory diagnostics are described. Laboratory diagnostics includes such biochemical markers as PAPP-A, PIGF, VEGF, sFlt-1, sEng, NSE; instrumental diagnostics consists of ultrasound evaluation of placental structure, ultrasound dopplerometry of uterine arteries and determination of the index of vascularization of the placenta. Not all methods of the examination presented by the author have diagnostic value in the clinical use. Biochemical markers present the most accurate diagnostic picture. It is necessary to evaluate sFlt-1, PIGF and other markers in dynamics since their change with the increase in the gestation age differs significantly from the change in those in women with normal pregnancy.
Eristova S.K. Saida Kh.
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
METHODS OF PRECLINICAL DIAGNOSIS OF PREECLAMPSIA. COMPARISON OF BIOCHEMICAL AND INSTRUMENTAL METHODS OF EXAMINATION
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 5, № 3 С. 128-131
2018
преэклампсия
preeclampsia
скрининг
screening
плацентарный фактор роста
placental growth factor
маркеры
markers
fms-подобная тирозинкиназа-1
fms-like tyrosine kinase-1
фактор роста эндотелия сосудов
vascular endothelial growth factor
допплерометрия маточных артерий
dopplerometry of uterine arteries
Статья
Обзор
The review presents current information on the predictive diagnosis of preeclampsia. The data of instrumental and laboratory diagnostics are described. Laboratory diagnostics includes such biochemical markers as PAPP-A, PIGF, VEGF, sFlt-1, sEng, NSE; instrumental diagnostics consists of ultrasound evaluation of placental structure, ultrasound dopplerometry of uterine arteries and determination of the index of vascularization of the placenta. Not all methods of the examination presented by the author have diagnostic value in the clinical use. Biochemical markers present the most accurate diagnostic picture. It is necessary to evaluate sFlt-1, PIGF and other markers in dynamics since their change with the increase in the gestation age differs significantly from the change in those in women with normal pregnancy.