Influence of ADRB2 gene polymorphism on the development of preterm birth in women of different ethnic groups
Proklova G.F., Chilova R.A., Sokova E.A., Kazakov R.E.
Архив акушерства и гинекологии им. В.Ф. Снегирева
Т. 7, № 3, С. 116-119
Опубликовано: 23 2020
Тип ресурса: Статья
DOI:10.17816/2313-8726-2020-7-3-116-119
Аннотация:
Preterm birth remains an acute medical and socio-economic problem. The successful course of pregnancy and its completion by timely delivery is directly dependent on an adequate balance of immune interactions between the mother and the fetus throughout the pregnancy, respectively, any failure of this system can lead to catastrophic consequences. The level of cytokine expression is genetically determined. Polymorphism of a gene affects the level of cytokines in its expression and functionality. Thus, polymorphism of cytokine genes can have an effect on the development of various pregnancy complications leading to its premature termination.
Язык текста: Русский
ISSN: 2313-8726
Proklova G.F. Gyuzel F.
Chilova R.A. Raisa A.
Sokova E.A. Elena A.
Kazakov R.E. Ruslan E.
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
Clinical Pharmacology Center “Scientific Center for Expertise of Medical Devices”, Ministry of Health of Russia
Influence of ADRB2 gene polymorphism on the development of preterm birth in women of different ethnic groups
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 7, № 3 С. 116-119
2020
преждевременные роды
preterm birth
токолитическая терапия
tocolytic therapy
полиморфизм гена ADRB2
ADRB2 gene polymorphism
Статья
Preterm birth remains an acute medical and socio-economic problem. The successful course of pregnancy and its completion by timely delivery is directly dependent on an adequate balance of immune interactions between the mother and the fetus throughout the pregnancy, respectively, any failure of this system can lead to catastrophic consequences. The level of cytokine expression is genetically determined. Polymorphism of a gene affects the level of cytokines in its expression and functionality. Thus, polymorphism of cytokine genes can have an effect on the development of various pregnancy complications leading to its premature termination.