Аннотация:
Thrombotic microangiopathy (TMA) is a clinical and morphological syndrome, which is based on damage of the endothelium. Clinically, TMA is characterized by a triad of symptoms: thrombocytopenia, microangiopathic hemolytic anemia, and target organ damage. In obstetric practice, TMA most often occurs with preeclampsia or HELLP syndrome, atypical HUS, TTP. The review presents the basic differential criteria for the diagnosis of TMA during pregnancy and after childbirth, as well as the management of patients.
Kukina P.I. Polina I.
Moskatlinova A.V. Anastasiya V.
Bogomazova I.M. Irina M.
Timokhina E.V. Elena V.
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
Differential diagnosis of obstetric thrombotic microangiopathy: a review
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 8, № 2 С. 67-74
2021
беременность
pregnancy
преэклампсия
тромботическая тромбоцитопеническая пурпура
гемолитико-уремический синдром, типичный и атипичный
preeclampsia
HELLP-синдром
HELLP-синдром
HELLP syndrome
HELLP syndrome
thrombotic thrombocytopenic purpura
hemolytic-uremic syndrome, typical and atypical
Статья
Обзор
Thrombotic microangiopathy (TMA) is a clinical and morphological syndrome, which is based on damage of the endothelium. Clinically, TMA is characterized by a triad of symptoms: thrombocytopenia, microangiopathic hemolytic anemia, and target organ damage. In obstetric practice, TMA most often occurs with preeclampsia or HELLP syndrome, atypical HUS, TTP. The review presents the basic differential criteria for the diagnosis of TMA during pregnancy and after childbirth, as well as the management of patients.