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Premature rupture of the fetal membranes during premature pregnancy. Management: reality and prospects

Timokhina E.V., Lebedev V.A., Karpova A.M., Kurbanzade P.F., Mikheeva M.V.
Архив акушерства и гинекологии им. В.Ф. Снегирева
Т. 8, № 2, С. 93-100
Опубликовано: 01 2021
Тип ресурса: Статья

DOI:10.17816/2313-8726-2021-8-2-93-100

Аннотация:

Premature rupture of the fetal membranes is a complication of pregnancy, causing premature labour and birth of a premature newborn. Premature birth rate consist of 6 to 12[%].

<strong><em>MATERIALS AND METHODS:</em></strong> We perform a retrospective analysis of 71 cases of patients with a premature rupture of the fetal membranes with active and expectant management and perinatal outcomes. The 1st group consisted of 19 patients with a gestation age of 2228 weeks, the 2nd group ― 52 patients with a gestation age of 2934 weeks.

<strong><em>RESULTS:</em></strong> The duration of the period between rupture of membranes and delivery in patients of the first group (2228 weeks) was: up to 48 hours ― 3 patients, 48 hours 14 days ― 15 patients, more than 14 days ― 1 patient. In patients of the second group (2934 weeks), respectively: up to 48 hours ―17 patients, 48 hours 14 days ― 30 patients, more than 14 days ― 5 patients. The duration of expectant management for PRFM in premature pregnancy is determined by the duration of pregnancy, the condition of the mother of the fetus, the presence of clinical and laboratory signs of chorioamnionitis, the amount and changing of the volume of amniotic fluid. The management of prolongation preterm pregnancy led to the fact that the gestational age at the time of delivery compared to the time of hospitalization significantly increased. In the group of patients, 2228 weeks gestation, the increase averaged 6.7 days, the maximum increase was 25 days, in the group of patients 2934 weeks gestation, the increase averaged 6.8 days, the maximum increase in gestational age was 35 days.

<strong><em>CONCLUSION:</em> </strong>The expectant management of premature pregnancy in PRFM allows to increase the gestational age (by an average of 6.8 days), to increase the weight of the fetus, to reduce perinatal mortality, to reduce the need for prematures in mechanical ventilation by more than half, to ensure a high level of discharge of newborns home.

Язык текста: Русский
ISSN: 2313-8726
Timokhina E.V. Elena V.
Lebedev V.A. Vladimir A.
Karpova A.M. Alina M.
Kurbanzade P.F. Parvin F.
Mikheeva M.V. Mariya V.
Первый МГМУ им. И.М. Сеченова МЗ РФ
I.M. Sechenov First Moscow State Medical University
Premature rupture of the fetal membranes during premature pregnancy. Management: reality and prospects
Текст визуальный электронный
Архив акушерства и гинекологии им. В.Ф. Снегирева
Eco-Vector
Т. 8, № 2 С. 93-100
2021
беременность
pregnancy
преждевременные роды
premature birth
преждевременный разрыв плодных оболочек (ПРПО)
premature rupture of the fetal membranes (PRFM)
преждевременное излитие околоплодных вод (ПИОВ)
premature discharge of amniotic fluid
недоношенность
prematurity
Статья

Premature rupture of the fetal membranes is a complication of pregnancy, causing premature labour and birth of a premature newborn. Premature birth rate consist of 6 to 12[%].

<strong><em>MATERIALS AND METHODS:</em></strong> We perform a retrospective analysis of 71 cases of patients with a premature rupture of the fetal membranes with active and expectant management and perinatal outcomes. The 1st group consisted of 19 patients with a gestation age of 2228 weeks, the 2nd group ― 52 patients with a gestation age of 2934 weeks.

<strong><em>RESULTS:</em></strong> The duration of the period between rupture of membranes and delivery in patients of the first group (2228 weeks) was: up to 48 hours ― 3 patients, 48 hours 14 days ― 15 patients, more than 14 days ― 1 patient. In patients of the second group (2934 weeks), respectively: up to 48 hours ―17 patients, 48 hours 14 days ― 30 patients, more than 14 days ― 5 patients. The duration of expectant management for PRFM in premature pregnancy is determined by the duration of pregnancy, the condition of the mother of the fetus, the presence of clinical and laboratory signs of chorioamnionitis, the amount and changing of the volume of amniotic fluid. The management of prolongation preterm pregnancy led to the fact that the gestational age at the time of delivery compared to the time of hospitalization significantly increased. In the group of patients, 2228 weeks gestation, the increase averaged 6.7 days, the maximum increase was 25 days, in the group of patients 2934 weeks gestation, the increase averaged 6.8 days, the maximum increase in gestational age was 35 days.

<strong><em>CONCLUSION:</em> </strong>The expectant management of premature pregnancy in PRFM allows to increase the gestational age (by an average of 6.8 days), to increase the weight of the fetus, to reduce perinatal mortality, to reduce the need for prematures in mechanical ventilation by more than half, to ensure a high level of discharge of newborns home.