Endogenous inhibitors of the Na, K-ATPase in preeclampsia
Lopatin D.A., Ailamazian E.K., Dmitrieva R.I., Fedorova O.V., Kolodkin N.I., Bagrov A.Y.
Журнал акушерства и женских болезней
Т. 48, № 5S, С. 103
Опубликовано: 15 1999
Тип ресурса: Статья
Аннотация:
[strong]Objectives: [/strong]Previously we have shown, that mammalian tissues contain a steroidal inhibitor of Na, K-ATPase which is similar to Amphibian vasoconstrictor hormone, marinobufagenin (MBG). The mammalian MBG is implicated in plasma volume dependent forms of hypertension. We compared plasma levels of MBG, in normotensive pregnancy and in preeclampsia with that of ouabain-like compound (OLC), and characterized the partially purified MBG immunoreactive factor from preeclamptic plasma.
Язык текста: Русский
ISSN: 1684-0461
Lopatin D.A.
Ailamazian E.K.
Dmitrieva R.I.
Fedorova O.V.
Kolodkin N.I.
Bagrov A.Y.
D.O. Ott Institute of Obstetrics and Gynecology
Sechenov Institute of Evolutionary Physiology and Biochemistry
Verta peptids inc.
National Institute on Aging
Endogenous inhibitors of the Na, K-ATPase in preeclampsia
Текст визуальный электронный
Журнал акушерства и женских болезней
Eco-Vector
Т. 48, № 5S С. 103
1999
endogenous inhibitors
Na, K-ATPase
preeclampsia
Статья
[strong]Objectives: [/strong]Previously we have shown, that mammalian tissues contain a steroidal inhibitor of Na, K-ATPase which is similar to Amphibian vasoconstrictor hormone, marinobufagenin (MBG). The mammalian MBG is implicated in plasma volume dependent forms of hypertension. We compared plasma levels of MBG, in normotensive pregnancy and in preeclampsia with that of ouabain-like compound (OLC), and characterized the partially purified MBG immunoreactive factor from preeclamptic plasma.