Аннотация:
Enteroviruses are among the best studied small non-enveloped enteric RNA viruses. Most enteroviruses are easy to isolate in cell culture, and many non-polio enterovirus strains were archived worldwide as a byproduct of the WHO poliovirus surveillance system. Common outbreaks and epidemics, most prominently the epidemic of hand-foot-and-mouth disease with severe neurological complications in East and South-East Asia, justify practical interest of non-polio enteroviruses. As a result, there are over 50 000 enterovirus nucleotide sequences available in GenBank. Technical possibilities have been also improving, as Bayesian phylogenetic methods with an integrated molecular clock were introduced a decade ago and provided unprecedented opportunities for phylogenetic analysis. As a result, hundreds of papers were published on the molecular epidemiology of enteroviruses. This review covers the modern methodology, structure, and biases of the sequence dataset available in GenBank. The relevance
Ключевые слова:
emerging virus; enterovirus; evolution; outbreak
Enterovirus; human; molecular epidemiology; nonhuman; phylogeny; Review; virus mutation; virus virulence; biology; classification; DNA sequence; Enterovirus; Enterovirus infection; epidemic; genetic variation; genetics; genotype; global health; isolation and purification; molecular epidemiology; phylogeny; procedures; virology; Computational Biology; Disease Outbreaks; Enterovirus; Enterovirus Infections; Genetic Variation; Genotype; Global Health; Humans; Molecular Epidemiology; Phylogeny; Sequence Analysis, DNA
Lukashev A. N. Aleksandr Nikolaevich 1977-
Vakulenko Yu. A. Yuliya Aleksandrovna 1994-
Turbabina N. A. Natal`ya Aleksandrovna 1981-
Devyatkin A. A. Andrej Andreevich 1990-
Doktor D. Ya. F. Dreksler Yan Feliks 1976-
Лукашев А. Н. Александр Николаевич 1977-
Вакуленко Ю. А. Юлия Александровна 1994-
Турбабина Н. А. Наталья Александровна 1981-
Девяткин А. А. Андрей Андреевич 1990-
Доктор Д. Я. Ф. Дрекслер Ян Феликс 1976-
Molecular epidemiology and phylogenetics of human enteroviruses: Is there a forest behind the trees?
Текст визуальный непосредственный
Reviews in Medical Virology
John Wiley & Sons
Vol.28, Issue6 Num.e2002
2018
Обзор
emerging virus enterovirus evolution outbreak
Enterovirus human molecular epidemiology nonhuman phylogeny Review virus mutation virus virulence biology classification DNA sequence Enterovirus Enterovirus infection epidemic genetic variation genetics genotype global health isolation and purification molecular epidemiology phylogeny procedures virology Computational Biology Disease Outbreaks Enterovirus Enterovirus Infections Genetic Variation Genotype Global Health Humans Molecular Epidemiology Phylogeny Sequence Analysis, DNA
Enteroviruses are among the best studied small non-enveloped enteric RNA viruses. Most enteroviruses are easy to isolate in cell culture, and many non-polio enterovirus strains were archived worldwide as a byproduct of the WHO poliovirus surveillance system. Common outbreaks and epidemics, most prominently the epidemic of hand-foot-and-mouth disease with severe neurological complications in East and South-East Asia, justify practical interest of non-polio enteroviruses. As a result, there are over 50 000 enterovirus nucleotide sequences available in GenBank. Technical possibilities have been also improving, as Bayesian phylogenetic methods with an integrated molecular clock were introduced a decade ago and provided unprecedented opportunities for phylogenetic analysis. As a result, hundreds of papers were published on the molecular epidemiology of enteroviruses. This review covers the modern methodology, structure, and biases of the sequence dataset available in GenBank. The relevance